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Psychological well-being is usually associated with levels of optimal functioning that include, not only the relationship between the subject and others, but also internal attitudes such as mastery and personal growth. It was around this context that the present research was proposed, whose main objective was to describe the psychological well-being of Montevidean adolescents using the Casullo’s BIEPS-J scale. A cross-sectional, correlational and non-experimental study was carried out with the participation of 473 adolescents from public and private high schools in Montevideo. The scores of psychological well-being and their dimensions were compared through parametric techniques such as t-test and oneway ANOVA, but also through robust tools for heteroscedasticity such as Welch’s t-test and Welch’s ANOVA. The association between variables was measured with the chi-square test of independence, by calculating Fisher’s exact statistic when the assumptions of that test were not met. Significant differences were found in acceptance by sex (p=4×10-6) and by age grouped into links (p=0.003), acceptance (p=0.036) and psychological well-being (p=0.028). A statistically significant relationship was also found between sex and acceptance (p=1,28×10-4) and between sex and psychological well-being (p=0.007). The results are discussed from the multidimensional well-being postulates and from the adolescent evolutionary indicators of the life cycle. In this sense, the adolescent sample presents high values of psychological well-being, expressed in an adequate functioning in control, acceptance, links and projects. A possible differential trajectory of psychological well-being in its dimensions according to sex is suggested. [ABSTRACT FROM AUTHOR]