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Nutrition education at school can contribute to developing healthy nutritional behaviours in schoolchildren. This paper critically reflects on how participatory action research (PAR) empowered university researchers and a school community to co-develop a school-based nutrition education programme (SBNEP) that promotes healthy nutritional behaviours in basic-level schoolchildren (Grades 1-8). This study followed PAR as the methodological approach, where university researchers collaborated with the school stakeholders, also called 'co-researchers', to co-develop a SBNEP. This study was conducted in a public school located in the Chitwan district of Nepal from June 2018 to August 2022. The study involved basic-level schoolteachers, fourth to eighth-grade students and their parents/guardians, school leaders, and the PAR committee members as the co-researchers. The study used in-depth interviews, focus groups, participant observation, informal talks, and bridging-the-gap workshop methods. The interpretive phenomenological method was used to explain the meaning of the data. The findings of the study reflect that exploring the needs for good nutritional behaviours, prioritising them, and co-designing the SBNEP utilising the PAR methodology is a time-consuming project since it demands prolonged fieldwork, self-motivation, commitment, action with critical reflection (praxis), dialogic relation, and negotiation skills from both researchers and co-researchers. The study recommends that basic-level schoolteachers and researchers consider applying SBNEP using a participatory framework for transformational change in students' nutritional behaviours.

This paper reflects upon and discusses the case of a participatory action research project in a public school in Nepal with the aim of exploring the possibilities for participatory approaches to contextualised teaching and learning. We discuss how research-degree students and school stakeholders involved in participatory needs assessment identified the need for contextualised teaching and learning and the participatory and generative model of contextualised teaching and learning we initiated in response. However, at the end of three different participatory action research (PAR) cycles, we came to an understanding that, for sustainable pedagogical reforms, even buzz words like 'participatory' and 'shifts in perspectives' have some limitations. In a bureaucratic schooling structure, like that in Nepal, pedagogical innovations for contextualised teaching and learning have to negotiate pre-structured schooling cultures, and therefore, any change in individual and group perspectives has to be accompanied by a shift in regular schooling design, from linear closedness to ecological openness. Otherwise, the innovations for contextualised teaching and learning are unlikely to be sustained in the face of the dominant practice architecture.

This study used a self-and peer-assessment activity in Moodle, a learning management system, to investigate the self-and peer-assessment abilities of student-teachers. To enhance self- and peer-assessment in some author-taught courses, students submitted online texts graded by their peers using a grading scale determined by course facilitators as a rubric or aspects approved by course facilitators. This study aimed to design and investigate self-, and peer-assessment activities among 18 students (10 boys and 8 girls) enrolled in one of Kathmandu University Schools of Education's MPhil/Ph.D. program in STEAM (Science, Technology, Engineering, Arts and Mathematics) in Nepal in 2021. The objective was to identify the most effective strategies for involving student-teachers in the learning and assessment processes using self- and peer-assessment as a learning and assessment tool using action research as a research methodology. This study followed the procedures of planning, intervening, evaluating effectiveness, and sharing learning processes within the action research framework. In order to achieve the research objectives, this article discussed some of the Workshop activity's key strengths and applications within cognitive and constructivist theoretical frameworks, among others. The article concluded by outlining the key advantages of self-and peer assessment in increasing student engagement and improving higher-order skills. These are analytical, and evaluation skills developed through the process of grading self- and peer submissions on a variety of criteria (aspects). The findings show that students are responsible for learning, have metacognitive skills, and use a dialogical, shared teaching and learning model. For higher education, it is a useful tool for self-and peer- assessment.

The existing Western modern worldviews (i.e., post/positivism) or Western induced paradigm(e.g., critical and postmodern) seem insufficient for ensuring harmonious learning spaces in the context of the continuous professional development of Nepali school teachers. In this paper, we discuss context-responsive sociocultural perspectives of multiple Eastern wisdom traditional (EWT) belief systems such as prasna (question), kalaa (art), and artha (meaning) that contribute to harmonious professional learning spaces (inner and outer) for teachers in Nepal. Then, we introduce gyana/pragya, an integral paradigm, as a multiparadigmatic research design space for creating and sustaining harmony in the professional setting and within coresearchers. This research explores the possibility of conducting educational research (e.g., Teachers Professional Development) by adapting multiple EWT belief systems. Finally, we share enhanced harmony, an inherent quality of teachers and teacher educators for professional development.

Facebook Live has become a means of teaching and learning in many parts of the world. This paper, thus, reports an examination of teaching English through Facebook Live and students' experiences of learning on it in the COVID-19 pandemic. It as participatory action research employed observation of self-managed Facebook Live streaming, and an online semi-structured interview with students and parents. The intervention of Facebook Live consisted of three strategies: pre-recorded video streaming, live teaching and a combination of both. This paper reports on how students in absence of a physical classroom learned English through Facebook Live, developed communicative skills and gained ICT skills. Although the teacher's lessons on Facebook Live were appreciated by students and parents as students could get ideas for speaking English, students expressed concerns if they could interact with the teacher and friends. Facebook Live associated with videoconferencing tools, however, can complement physical classroom learning in crises and normal situations.

This paper explores the paradigm shift in using ICT tools while teaching mathematics remotely within the TPACK framework. Remote teaching is not only one of the primary modes of teaching and learning in the present context throughout the world but the transition from paper to the digital world, where mathematics teachers struggle to visualize the content concisely and clearly. This paper focuses on promoting pedagogy and learning and learner empowerment by emphasizing autonomy and engagement rather than technology. The ethos of this paper is all about encouraging the mathematics teachers to promote the students for quality engagement while teaching remotely. However, all the remotely leading ICT tools require some techniques and methodologies, thereby the mathematics teachers' skill, experience, and expertise. Those skills, experiences, and expertise will be developed by excelling in mathematics teachers' ICT tools. This paper shall be one of the guiding principles for mathematics teachers (but not limited to) while dealing with the mathematics content remotely and/or in any other mode.

The 2015 constitution of Nepal declared Nepal to be a Federal, Democratic, and Republic nation. The constitution has provided local governments the right to manage school education, and the 2017 Local Government Operation Act of Nepal has outlined the roles and responsibilities of local governments in taking guardianship of school education. Since 2017, Nepal has been in the process of institutionalising decentralised governance practices, but this is proceeding at a slow pace. Unprecedently, from early 2020, the COVID-pandemic hit hard the lives of Nepali people, and Nepali education suffered greatly. The pandemic has brought several opportunities for the government to devolve the management system of school education to local levels. This article is based upon the analysis of the six newly introduced plans, regulations, and guidelines in Nepali education, that aim to continue school education amid the COVID-pandemic. These newly introduced polices have significantly acknowledged and mobilised the local strengths in educational management. This research supports a new academic discussion on governance ideas of the Nepalese education system, induced by the COVID-19 pandemic.

The purpose of this study was to explore the critical life-events of the first author's journey of learning and teaching mathematics that prompted critical thinking about his past experiences as a student and teacher. It portrays a paradigmatic shift from a traditionalist thinker to a constructivist actor in the classroom from the critical life-events within and out of classroom experiences by using autoethnography as the writing and research genre by connecting his personal experiences in the social, cultural, and teaching/learning contexts of Nepal. The major themes emerged from the autoethnography were--Thinking Narratively: Joining a School and Dropping Out; Thinking Narratively: Back to School and Dropping In; Thinking Interpretively: Dropping out of School; Thinking Poetically: Dropping in School; and Nightmare of the First Teaching: A Pedagogical Boomerang. These themes portrayed a pedagogical boomerang in learning and teaching mathematics from a remote village in Western Nepal to the neighborhood of the capital city Kathmandu.

The integrated information and communication technology (ICT) as the pedagogical content has led to great opportunities and challenges in the educational ideas and practices. This study explores the contextual use of the ICT integrated pedagogy in Tribhuvan University. The detail analysis has been made on the basis of primary and secondary data collected from the respondents, and literature respectively. The qualitative approach, phenomenological design, constructive paradigm, descriptive methodology and inductive data analysis system have been applied for this study. The ICT technique that teachers apply as a tool or as pedagogy in the classes are analyzed. On the basis of it, the shortcomings, improvements and possible recommendations for the improvement of the existing scenario have been presented.

For several years, science and art have been viewed as separate entities in school education in Nepal. The dominant discourse on science was regulated by Western Modern Worldview (WMW), assuming that seeking universal truth should be the central aim of the exploration. In this article, science refers to the absolutist/rigid nature of different disciplines (such as Science and Mathematics) from the perspectives of Newtonian science, whereas art is viewed from three dimensions; literary arts (i. e. narratives, storing), visual arts (i.e., images, painting, sculpture) and performing arts (i.e., role play, drama). This paper argues that science and arts, as ways of knowing, should be taken as complements of each other. This literature-based argumentative paper also incorporates the lead author's experiences using art as/for pedagogical approaches in collaboration with schoolteachers. At the same time, the authors also argue the role of critical reflection to acknowledge both science and art as epistemology. The authors have used Dewey's perspectives on the roles of art for experiencing in education. Also, the notion of Mezirow's Transformative Learning is helpful as an influential lens to showcase the ever-changing thoughts in the transformation continuum. To set the context for the argumentation, the authors discussed the existing Nepali school education system, focused on curricula and pedagogical perspectives. The paper is helpful for teachers, teacher educators, and researchers to critically reflect on their own beliefs and practices in terms of viewing the different perspectives on STEM subjects and the inseparable relationship of science and art for knowledge generation and pedagogical application.

This paper examines different layers of participation while conducting Participatory Action Research (PAR). In the journey of three years of fieldwork with teachers, many realizations were made about becoming co-researchers and engaging in a collaborative knowledge-building process for developing an engaged pedagogical approach. The paper had two purposes: a) exploring the different layers of participation in PAR, and b) documenting the lead researcher's continuous professional learning in understanding PAR. The lead researcher proposed "ignoring" to "autonomous" participation as levels. The lead researcher also changed from overly influencing roles on PAR to accepting co-researchers' voices and respecting their efforts for sustainable change.

This article investigates perceived existing classroom practices in mathematics pedagogy and the impact on Nepalese mathematics teachers' understanding and uses of questioning. For this study, a narrative inquiry approach has been used to focus on the experiences of six mathematics teachers working in schools in Kathmandu Valley, Nepal. A criterion-based selection strategy was used to choose research participants for this research (Roulston, 2010). This article aims to examine the complexities of mathematics classroom experiences by gaining insight into the use of questioning. This inquiry utilizes a variety of theoretical lenses, including sociological perspectives and behaviorists through constructivist approaches to categorize questioning using the criteria of expertise, critical pedagogical perspectives and algorithmic and daily life practices. Through this methodological approach an analysis of relative power relations in mathematics classroom established through teacher perspective in questioning is made. This study is framed through the research question: How do teachers narrate their experience of understanding and usage of questioning in relation to mathematics pedagogy? Subscribing to a narrative inquiry for meaning-making, this article thus studied six mathematics teachers' voices and experiences to explore classroom power relationship in the context of whose experiences are valued and whose voice can be heard in during student questioning. In conclusion it was found that the majority of the studied mathematics teachers seem to be conformist to a perceived appropriate method of questioning at the beginning of their teaching career but become nonconformist, defined as being more flexible in questioning technique later in their career. Further it was found that the majority of the research participants asked more questions within the simple to complex level with greater focus on simple (low level) questioning due to a belief that this encourages students to engage in mathematical discussion.

The purpose of this study was to explore mathematics teachers' perception of social justice in mathematics classrooms. We applied interpretive qualitative method for data collection, analysis, and interpretation through iterative process. We administered in-depth semi-structured interviews to capture the perceptions of three mathematics teachers about social justice in mathematics classroom at three public secondary schools in Kathmandu. We carried out multiple layers of thematic analysis and interpretation of the narratives from the interview data. Altogether five themes on perception of social justice emerged from the analysis of the data. These themes were associated with - equality, equity, fairness, social process, and caring students. Implications of the study have been discussed at the end.

Background: Multimorbidity is rising in low-and middle-income countries such as Nepal, yet the research has not gained pace in this field. We aimed to systematically review the existing multimorbidity literature in Nepal and estimate the prevalence and map its risk factors and consequences. Methods: We reviewed data collated from PubMed, Embase and CINAHL by including original studies that reported prevalence of multimorbidity in Nepal. The quality of included studies was assessed using the Appraisal Tool for Cross-sectional Studies. The summary of the review is presented both qualitatively as well as through meta-analysis to give pooled prevalence. We prospectively registered in PROSPERO (CRD42024499598). Results: We identified 423 studies out of which seven were included in this review. All studies were conducted in a community setting except one which was hospital based. The prevalence reported across various studies ranged from 13.96% to 70.1%. The pooled prevalence of multimorbidity was observed to be 25.05% (95% CI: 16.99 to 34.09). The number of conditions used to assess multimorbidity ranged from four to nine. The major risk factors identified were increasing age, urban residence, and lower literacy rates. Conclusion: A wide variance in the prevalence of multimorbidity was observed. Moreover, multimorbidity assessment tool/conditions considered for assessing multimorbidity were heterogeneous. [ABSTRACT FROM AUTHOR]

Nepal holds a high ichthyofaunal diversity, nevertheless, the molecular study of Nepalese fish is still in its early stages. The first record of a cyprinid fish species the Garra kempi Hora, 1921 for Nepal was reported from eastern Nepal's Lohandra River. Both morphology and molecular data affirmed the existence of G. kempi in Nepal's aquatic system. This species was previously reported from China (Tibet) and northern India. The maximum likelihood phylogenetic analysis and pairwise genetic distance based on Kimura 2 parameters using cytochrome oxidase subunit 1 (COI) segment sequences (665 bp) also confirmed the identity of the species as G. kempi. The COI sequences of specimens from Nepal formed a monophyletic clade with the sequence of G. kempi from northeastern India and the two contained a pairwise genetic distance of 1.8% only. The new record of G. kempi from Nepal warrants a detailed ichthyofaunal survey for documenting the fish diversity in Nepal. [ABSTRACT FROM AUTHOR]

Background: Improvements in standard precaution related to infection prevention and control (IPC) at the national and local-level health facilities (HFs) are critical to ensuring patient's safety, preventing healthcare-associated infections (HAIs), mitigating Antimicrobial Resistance (AMR), protecting health workers, and improving trust in HFs. This study aimed to assess HF's readiness to implement standard precautions for IPC in Nepal. Methods: This study conducted a secondary analysis of the nationally-representative Nepal Health Facility Survey (NHFS) 2021 data and used the Service Availability and Readiness Assessment (SARA) Manual from the World Health Organization (WHO) to examine the HF's readiness to implement standard precautions for IPC. The readiness score for IPC was calculated for eight service delivery domains based on the availability of eight tracer items: guidelines for standard precautions, latex gloves, soap and running water or alcohol-based hand rub, single use of standard disposal or auto-disable syringes, disinfectant, safe final disposal of sharps, safe final disposal of infectious wastes, and appropriate storage of infectious waste. We used simple and multiple linear regression and quantile regression models to examine the association of HF's readiness with their characteristics. Results were presented as beta (β) coefficients and 95% confidence interval (95% CI). Results: The overall readiness scores of all HFs, federal/provincial hospitals, local HFs, and private hospitals were 59.9±15.6, 67.1±14.4, 59.6±15.6, and 62.6±15.5, respectively. Across all eight health service delivery domains, the HFs' readiness for tuberculosis services was the lowest (57.8±20.0) and highest for delivery and newborn care services (67.1±15.6). The HFs performing quality assurance activities (β = 3.68; 95%CI: 1.84, 5.51), reviewing clients' opinions (β = 6.66; 95%CI: 2.54, 10.77), and HFs with a monthly meeting (β = 3.28; 95%CI: 1.08, 5.49) had higher readiness scores. The HFs from Bagmati, Gandaki, Lumbini, Karnali and Sudurpaschim had readiness scores higher by 7.80 (95%CI: 5.24, 10.36), 7.73 (95%CI: 4.83, 10.62), 4.76 (95%CI: 2.00, 7.52), 9.40 (95%CI: 6.11, 12.68), and 3.77 (95%CI: 0.81, 6.74) compared to Koshi. Conclusion: The readiness of HFs to implement standard precautions was higher in HFs with quality assurance activities, monthly HF meetings, and mechanisms for reviewing clients' opinions. Emphasizing quality assurance activities, implementing client feedback mechanisms, and promoting effective management practices in HFs with poor readiness can help to enhance IPC efforts. [ABSTRACT FROM AUTHOR]

Nutrition education at school can contribute to developing healthy nutritional behaviours in schoolchildren. This paper critically reflects on how participatory action research (PAR) empowered university researchers and a school community to co-develop a school-based nutrition education programme (SBNEP) that promotes healthy nutritional behaviours in basic-level schoolchildren (Grades 1–8). This study followed PAR as the methodological approach, where university researchers collaborated with the school stakeholders, also called 'co-researchers', to co-develop a SBNEP. This study was conducted in a public school located in the Chitwan district of Nepal from June 2018 to August 2022. The study involved basic-level schoolteachers, fourth to eighth-grade students and their parents/guardians, school leaders, and the PAR committee members as the co-researchers. The study used in-depth interviews, focus groups, participant observation, informal talks, and bridging-the-gap workshop methods. The interpretive phenomenological method was used to explain the meaning of the data. The findings of the study reflect that exploring the needs for good nutritional behaviours, prioritising them, and co-designing the SBNEP utilising the PAR methodology is a time-consuming project since it demands prolonged fieldwork, self-motivation, commitment, action with critical reflection (praxis), dialogic relation, and negotiation skills from both researchers and co-researchers. The study recommends that basic-level schoolteachers and researchers consider applying SBNEP using a participatory framework for transformational change in students' nutritional behaviours. [ABSTRACT FROM AUTHOR]

Exploring ways to develop a transformative curriculum vision for mathematics education that is inclusive to opposing perspectives and ideologies, this mindful inquiry explores "mindless" views embedded in the mathematics curriculum of Nepal; explores narrowly conceived disempowering assumptions within it; engages in dialectical interactional texturing among perspectives; and eventually emerges with its transformative potentiality. In so doing, this reflection on hegemonic worship of modernity identifies Newtonian reductionism, absolutism, and non-fluidity of language, serving mono-cultural perspectives as restraints underlying inclusive mathematics curriculum. Reflecting on this meaning-making, and in seeking an equilibrium view of reality, the inquiry hopefully offers pluralism, synergy, and montage as imperative in making mathematics education more meaningful.

Nepal holds a high ichthyofaunal diversity, nevertheless, the molecular study of Nepalese fish is still in its early stages. The first record of a cyprinid fish species the Garra kempi Hora, 1921 for Nepal was reported from eastern Nepal's Lohandra River. Both morphology and molecular data affirmed the existence of G. kempi in Nepal's aquatic system. This species was previously reported from China (Tibet) and northern India. The maximum likelihood phylogenetic analysis and pairwise genetic distance based on Kimura 2 parameters using cytochrome oxidase subunit 1 (COI) segment sequences (665 bp) also confirmed the identity of the species as G. kempi. The COI sequences of specimens from Nepal formed a monophyletic clade with the sequence of G. kempi from northeastern India and the two contained a pairwise genetic distance of 1.8% only. The new record of G. kempi from Nepal warrants a detailed ichthyofaunal survey for documenting the fish diversity in Nepal. [ABSTRACT FROM AUTHOR]

Summary: Programmes focused on buffer zones (BZs) and park revenue-sharing (PRS) are aimed at sharing protected area (PA) benefits with local communities to meet their development needs and, in turn, improve the PA–people relationship. However, whether and how these programmes improve public attitudes towards PAs is little understood. We assessed how residents perceive the benefit and burdens of Nepal's BZ programme, which shares up to 50% of PA revenue with communities, and how this process relates to their perceptions of change in the PA–people relationship since the BZ programme was implemented. Survey results from 2122 households in the BZs of six PAs showed that residents' perceptions of PA–people relationships had improved since the BZ programme's implementation. Furthermore, the perceived trend in the PA–people relationship was positively related to the perception of benefits and satisfaction with coordination between the PA and local government; it was negatively related to perceived burdens of BZ-related laws in rural development, history of damage/loss from wildlife and misunderstandings of the purpose behind BZ funds being given to local communities. These findings provide valuable insights for PA managers in Nepal and worldwide in designing new or improving existing mechanisms of benefit-sharing with local people and to improve PA–people relationships. [ABSTRACT FROM AUTHOR]

Introduction: Family planning (FP) is crucial for improving maternal and newborn health outcomes, promoting gender equality, and reducing poverty. Unmet FP needs persist globally, especially in South Asia and Sub-Saharan Africa leading to unintended pregnancies, unsafe abortions, and maternal fatalities. This study aims to identify the determinants of unmet needs for FP from a nationally representative survey. Methods: We analyzed the data of 11,180 currently married women from nationally representative Nepal Health Demographic Survey 2022. We conducted weighted analysis in R statistical software to account complex survey design and non-response rate. We conducted univariate and multivariable binary and multinomial logistic regression to assess association of unmet need for FP with independent variables including place of residence, province, ecological belt, ethnicity, religion, current age, participant's and husband's education, occupation, wealth quintile, parity, desire for child, and media exposure. Results: The total unmet FP need was 20.8% (95%CI: 19.7, 21.9) accounting 13.4% (95%CI: 12.5, 14.4) for unmet need for limiting and 7.4% (95%CI: 6.8, 8.0) for unmet for spacing. Lower odds of total unmet need for FP were present in 20–34 years and 35–49 years compared to <20 years, women belonging to Madhesi ethnic group (AOR: 0.78; 95%CI: 0.64, 0.95) compared to Brahmin/Chhetri, women from richest (AOR: 0.69; 95%CI: 0.56, 0.84), richer (AOR: 0.82; 95%CI: 0.68, 0.97) and middle wealth quintile (AOR: 0.82; 95%CI:0.70, 0.98) groups compared poorest wealth quintile group and women belonging to rural area (AOR: 0.89; 95%CI: 0.80, 0.99) compared to urban area. Higher odds of unmet need for FP were present among women with basic (AOR: 1.34; 95%CI: 1.17, 1.54), and secondary level (AOR: 1.32; 95%CI: 1.12, 1.56) education compared to women without education, among women from Madhesh (AOR: 1.56; 95%CI: 1.22, 1.98), Gandaki (AOR: 2.11; 95%CI: 1.66, 2.68), Lumbini (AOR: 1.97; 95%CI: 1.61, 2.42) and Sudurpashchim province (AOR: 1.64; 95%CI: 1.27, 2.10) compared to Koshi province and among women whose husband education was basic level (AOR:1.37; 95%CI: 1.15, 1.63), or secondary level (AOR: 1.32; 95%CI: 1.09, 1.60) education. Conclusion: Nepal faces relatively high unmet FP needs across various socio-demographic strata. Addressing these needs requires targeted interventions focusing on age, ethnicity, religion, education, and socio-economic factors to ensure universal access to FP services. [ABSTRACT FROM AUTHOR]

A subsurface investigation was conducted to assess the suitability of a site for potential tunnel construction, focusing on the determination of shear wave velocities (Vs) in subsurface materials. This study employed three distinct methods to analyze Vs in weathered soft rock: drilling mechanism, multichannel analysis of surface waves (MASW), and microtremor array measurement (MAM). Through the utilization of MASW and MAM, empirical relationships were established, enabling the determination of Vs based solely on soil type and depth, offering a practical alternative to the limitations of SPT N-Value, particularly when exceeding 50 blows. The comparison of Vs values obtained from these methods revealed a close alignment between empirical techniques and MASW/MAM, which proved to be cost-effective and an efficient alternative to drilling for comprehensive underground structure assessments. The reliability of MASW was further underscored through its comparison with existing empirical methods. Moreover, the empirical approach demonstrated its efficacy in predicting velocities in weathered soft rock within the Central Himalayan region of Nepal, thus enhancing the feasibility study of underground structures. Lastly, this study proposed a Vs-Depth correlation specifically tailored for highly weathered meta-sandstone bedrock resulting in clay and sandy soils. [ABSTRACT FROM AUTHOR]

This paper reflects upon and discusses the case of a participatory action research project in a public school in Nepal with the aim of exploring the possibilities for participatory approaches to contextualised teaching and learning. We discuss how research-degree students and school stakeholders involved in participatory needs assessment identified the need for contextualised teaching and learning and the participatory and generative model of contextualised teaching and learning we initiated in response. However, at the end of three different participatory action research (PAR) cycles, we came to an understanding that, for sustainable pedagogical reforms, even buzz words like 'participatory' and 'shifts in perspectives' have some limitations. In a bureaucratic schooling structure, like that in Nepal, pedagogical innovations for contextualised teaching and learning have to negotiate pre-structured schooling cultures, and therefore, any change in individual and group perspectives has to be accompanied by a shift in regular schooling design, from linear closedness to ecological openness. Otherwise, the innovations for contextualised teaching and learning are unlikely to be sustained in the face of the dominant practice architecture. [ABSTRACT FROM AUTHOR]

Bhaktapur city, one of the historical cities of Nepal, is among the old settlements within Kathmandu Valley that were frequently devastated during major earthquakes. Historical evidence clearly states the high seismic vulnerability of Bhaktapur. So, this study characterizes the free field of the Bhaktapur district in terms of periods. For this, the horizontal to vertical (H/V) technique was used to determine the predominant period of the study area, measuring microtremor data at 200 m × 200 m spacing in the core city area, whereas 400 m × 400 m spacing of measurement was done at the outskirts of the city with rare settlement. The spatial distribution map of the predominant period is prepared with the period obtained from 609 measuring points. The map shows that the predominant period ranges from 0.1 to 4 s and then categorized into four different zones—A (0.10–0.6 s), B (0.6–1.0 s), C (1.0–1.7 s), and D (1.7–4.0 s). The central parts of the study areas are spotted with longer periods (1.7–4.0 s), where the density of the dweller is high. The structural period of 28 reinforced concrete buildings was also determined to understand the level of danger of the buildings due to soil-structure resonance. The predominant period of the buildings ranges from 0.12 to 0.42 s. The possibility of soil structure resonance condition is higher for six buildings, medium for two buildings, and low for the rest of the buildings. The results can be applied to urban planning, seismic hazard mitigation, conservation, and restoration of heritage monuments. [ABSTRACT FROM AUTHOR]

The Education Act 1971 is the main policy document under which schools in Nepal are operated. With the change in political regime, this policy has been amended as per the ideology of the incoming regime. Although private schools started to show their influence in Nepal in the late 1980s, excessive growth of private schools began with the neoliberal policy adopted by the incoming political parties soon after Nepal became a multiparty democratic country in the early 1990s. However, with the Maoists becoming a dominant political force in the country in the late 1990s, several challenges in the operation of private schools began. Issues such as closing down or monitoring of private schools are now common mass media headlines. This paper analyses such a situation in the operation of private schools in Nepal. It uses primary sources of data collected via semi-structured interviews with teachers, administrators and principals of two private schools located in the capital city of Nepal, Kathmandu. It also uses secondary sources that include mass media output and other documentary sources such as documents from private schools' associations and government policy related to private schools. This study found that operation of private schools in Nepal is comparable to what Michel Foucault calls tolerated illegality.

Background: The psychosocial consequences of tuberculosis (TB) are key barriers to ending TB globally. We evaluated and compared stigma, depression, and quality of life (QoL) among people with TB diagnosed through active (ACF) and passive (PCF) case-finding in Nepal. Methods: We prospectively recruited adults with TB diagnosed through ACF and PCF in four districts of Nepal between August 2018 and April 2019. Participants were interviewed at 8–12 weeks (baseline) and 22–26 weeks (follow-up) following treatment initiation. TB stigma was measured using an adapted Van Rie Stigma Scale (0 = no stigma to 30 = highest stigma). Depression was measured using a locally-validated Patient Health Questionnaire (PHQ-9). Mild and major depression were indicated by PHQ-9 scores 5–9 and ≥ 10, respectively. QoL was measured using the EuroQoL 5-Dimension 5-level (EQ-5D-5L) from 0 to 1 (optimal QoL); and self-rated health from 0 to 100 (optimal self-rated health). Results: We recruited 221 participants (111 ACF; 110 PCF) with a mean age of 48 years (standard deviation [SD] = ± 16), of whom 147/221 (67%) were men. The mean TB stigma score was 12 (SD = 7.3) at baseline and 12 (SD = 6.7) at follow-up. The most commonly perceived elements of TB stigma at baseline were that people with TB experienced guilt (110/221, 50%) and feared disclosure outside their household (114/221, 52%). Self-rated health and EQ-5D-5L scores increased from baseline to follow-up (69.3 to 80.3, p < 0.001; 0.92 to 0.9, p = 0.009). Nearly one-third of participants (68/221, 31%) had mild or major depression at baseline. The proportion of participants with major depression decreased from baseline to follow-up (11.5% vs. 5%, p = 0.012). There was a moderate, significant positive correlation between depression and stigma scores (r = 0.41, p < 0.001). There were no differences found in TB stigma, self-rated health, QoL, or prevalence of mild/major depression between ACF and PCF participants. Conclusions: We found a substantial, persistent, and clustered psychosocial impact among adults with TB diagnosed through both ACF and PCF strategies in Nepal. These findings suggest an urgent need to develop effective, evidence-based psychosocial support interventions with the potential to be integrated with existing ACF strategies and routine TB service activities. [ABSTRACT FROM AUTHOR]

Background: Nepal has made incremental progress in improving coverage of maternal health services leading to improved health outcomes. Government and other health sector stakeholders have consistently considered dissemination of educational messages on maternal health through mass media. However, in Nepal's context, the media's influence on the uptake of maternal health services is less known. This study examines the links between media exposure and maternal health service use in Nepal. Method: Our analysis is based on the nationally representative Nepal Demographic and Health Survey (NDHS) 2022 data. We analyzed data from 1933 women aged 15–49 who had given birth in the two years preceding the survey. Weight analysis was performed to account for complex survey design. We presented categorical variables as frequency, percentage, and corresponding 95% Confidence Interval (CI). Univariable and multivariable logistic regression assessed the association between media exposure and maternal health service use, and the results are presented as crude (COR) and adjusted odds ratios (AOR) along with 95% CI. Results: Women exposed to internet use had 1.59 times [AOR = 1.59, 95% CI = 1.16, 2.19], and those exposed to radio and television health programs had 1.73 times [AOR = 1.73, 95% CI = 1.17, 2.56] higher odds of having four or more Antenatal Care (ANC) visits. Similarly, women exposed to mass media had 1.32 times [AOR = 1.32, 95% CI = 1.00, 1.74] and those exposed to health programs had 1.50 times [AOR = 1.50, 95% CI = 1.02, 2.21] higher odds of having an institutional delivery. However, mass media exposure, internet use, and health program exposure were not significantly associated with increased postnatal care of mother and newborn. Conclusion: Exposure to health programs and internet use are positively associated with four or more ANC visits. Exposure to mass media and health programs are positively associated with increased institutional delivery. Our findings imply that well-designed campaigns and awareness programs delivered through mass media platforms play a vital role in enhancing the uptake of maternal health services. [ABSTRACT FROM AUTHOR]

The Ramaroshan Lake Complex (RLC) in Sudurpaschim Province, Nepal, is a Himalayan lake cluster that holds significant ecological, economic, religious, and esthetic importance. This study aimed to provide a comprehensive characterization of the hydrochemical properties of water within the RLC and assess its suitability for irrigation purposes. A total of 38 water samples were collected from seven different lakes of the complex. The physicochemical parameters and major ions were then analyzed. The water samples from the RLC were alkaline, and based on total hardness, they ranged from soft to moderately hard categories. The presence of major ions included the following: Ca2+ > Na+ > Mg2+ > K+ > Fe3+ > NH4+ and HCO3− > Cl− > SO42− > NO3− > PO43−. The alkaline earth metals (Ca2+ and Mg2+) dominated the alkali metals (Na+ and K+) and weak acids (HCO3−) dominated the strong acids (Cl− and SO42−). The dominant hydrochemical facies of the lake water was a Ca-HCO3 type indicating a calcium carbonate type of lithology. Carbonate rock weathering was the most dominant process in influencing the hydrochemistry of the water. A high ratio of (Ca2++ Mg2+)/Tz+ and a lower ratio of (Na+ + K+)/Tz+ revealed the dominance of Ca2+ and Mg2+ resulting from carbonate weathering, with little contribution from silicate weathering. Different irrigation indices revealed the suitability of the RLC water for irrigation. The insights derived from this study are pivotal in safeguarding water quality and bolstering sustainability efforts. The study also furnishes foundational data crucial to an array of stakeholders including researchers and policymakers and significantly contributes to advancing water management strategies and fostering ecosystem conservation in the Himalayan freshwater lakes, particularly in the face of the overarching challenge posed by global climate change. [ABSTRACT FROM AUTHOR]

Introduction: The COVID-19 pandemic has led to physical and psychological complications and social consequences in the form of illness-related stigma. This study aimed (1) to assess the sociodemographic and clinical variable, as well as COVID-19 related knowledge and perception of persons admitted for COVID-19/Suspected COVID-19 in Nepal, (2) to determine their levels of COVID-19-related internalized stigma, depression, and anxiety symptoms, and (3) to evaluate the correlates of COVID-19-related internalized stigma. Materials and methods: It was a cross-sectional exploratory study with a convenience sample of 395 participants (306 confirmed cases, 89 suspected cases) conducted between July-October 2020 in four health facilities in Madhesh and Lumbini provinces of Nepal. We used a semistructured questionnaire to assess sociodemographic details, clinical information, COVID-19-related knowledge, perception, COVID-19-related internalized stigma, and the Hamilton Anxiety Depression Scale (HADS) in Nepali language. Descriptive statistics, correlation analyses, and linear regression analyses were performed. The level of statistical significance was considered at p < 0.05. Results: Around 23.3% of the patients had anxiety symptoms, 32.9% had depressive symptoms, and 20.3% had high COVID-19-related internalized stigma (mean ISMI score: 2.51-4.00). Linear regression analyses showed a significant positive association of COVID-19-related internalized stigma total score, with the following eight factors, i.e., no income in the past one month (p = 0.013), below average socioeconomic status (p = 0.004), anxiety symptoms (p = <0.001), depressive symptoms (p = <0.001), recent testing positive for COVID-19 (p = <0.001), involuntary admission (p = <0.001), prior experience of being in isolation and quarantine (p = 0.045), and those who blame others for COVID-19 (p = 0.025). Conclusion: COVID-19 survivors and suspects are vulnerable to symptoms of depression, anxiety, and COVID-19-related internalized stigma. For the first time from Nepal, our data suggests that COVID-19-related internalized stigma is associated with anxiety and depression symptoms, perceived below-average socioeconomic status, involuntary admission, prior experience of being in isolation and quarantine, recent COVID-19 positive report, self-blame, below-average socioeconomic status and no income in the past one month. Mitigating and preventing internalized stigma associated with a public health crisis such as COVID-19 is imperative by diagnosing and treating such mental health issues early and designing interventions and policies especially targeting vulnerable populations focusing on their economic background and socio-cultural beliefs. [ABSTRACT FROM AUTHOR]

Study was carried out to assess the farmer's perception on the importance of pollination and profitability analysis of citrus farming in Syangja district. A multistage random sampling technique was used to select the study areas and respondents from the study areas. Putalibazaar Municipality, Bhirkot Municipality and Waling Municipality of Syangja district were selected in consultation with the PMAMP of Syangja district. Similarly, 66 respondents were selected using the purposive random sampling to collect the data using the semi-structured questionnaire. The collected data were processed tabulated and analyzed using SPSS and MS-Excel. Descriptive statistics were used to analyze data. It was found that male population (80.3%) was dominant over female population (19.7%). The average cultivated land for citrus was found to be 9.984 ropani. Average productivity and average price per kg of citrus of sampled household was found to be 6.13 mt and Rs. 55/kg respectively. Benefit-cost ratio was found to be 2.51 where Labor cost account as the major cost among the total cost of production with average of Rs. 47735. Study found that only 19.7% of the farmers possessed a strong understanding of the concept of pollination. However, 56.1% of the population were found to keep beehive i.e action was taken to manage pollination knowingly or unknowingly but primary motive was to rear bee for honey rather than for managing the pollinators while remaining of the population took no action. Study conducted in Syangja district, Nepal revealed that substantial proportion. exceeding 63.6% of the local farmers lacked knowledge regarding crops dependent on pollinators for reproduction. Study found that 51.3% of participating farmers exhibited a low level of knowledge concerning climate change. Additionally, none of the respondents reported implementing practices specifically aimed at mitigating the impacts of climate change on their agricultural operations. A study investigating agroecological practices among farmers revealed that 71.2% employed both intercropping and mulching techniques. In contrast, 28.8% of the farmers solely utilized mulching as their ecological practice. [ABSTRACT FROM AUTHOR]

Exchange rate is an important macroeconomic variable which influence internal and external balance and indicates external competitiveness of an economy. It plays a role of catalyst for macroeconomic stability. The main objective of this research is to investigate the relationship of exchange rate with different macroeconomic variables such as GDP, inflation, interest rate, broad money supply, and trade openness in order to reveal significant determinants of exchange rate of Nepal. The research uses secondary annual average data obtained from NRB, WB, and IMF from time period of 1993 to 2022 AD. The study uses ADF test to test the stationarity of variables. ARDL approach to co-integration is used for estimation of long run relationship and ECM is applied for estimating short run relationship between dependent and independent variables. The study also uses CUSUM and CUSUM of square test to validate stability of coefficient of long run model. Results from ARDL bound co-integration test shows evidence of long run co-integration between dependent variable and regressors as calculated F-statistics (3.989) is greater than critical value for upper bound I(1). The results of estimated long run coefficients using ARDL approach shows that inflation and money supply have negative long run relation with exchange rate whereas GDP, interest rate and trade openness have a positive long run relation with exchange rate. The coefficient of the error term is found to be --0.33 using ECM. Results from ECM indicate positive and significant effect of interest rate on exchange rate in short run, while the effects of GDP, inflation, money supply, and trade openness are found insignificant in short runs. The findings of this study may aid policy makers of Nepal to formulate such monetary and fiscal policies that makes exchange rate less volatile and more productive for sustainable economic growth of the nation. [ABSTRACT FROM AUTHOR]

Any country's economic base is largely dependent on foreign trade. This research examines the relationship between imports and export and economic development. This research seeks to analyze the foreign trade growth trend and evaluate how Nepal's economy is influenced by exports, imports. The ARDL model has been applied to investigate the impact of foreign trade on Nepal's economic progress. The study draws on data from the years 2000/01 to 2022/23. Empirical evidence suggests that there is a stable long-term relationship between economic growth and foreign trade. [ABSTRACT FROM AUTHOR]

Background: With an increasing burden of stroke, it is essential to minimize the incidence of stroke and improve stroke care by emphasizing areas that bring out the maximum impact. The care situation remains unclear in the absence of a national stroke care registry and a lack of structured hospital-based data monitoring. We conducted this systematic review and meta-analysis to assess the status of stroke care in Nepal and identify areas that need dedicated improvement in stroke care. Methods: A systematic literature review was conducted to identify all studies on stroke epidemiology or stroke care published between 2000 and 2020 in Nepal. Data analysis was done with Statistical Package for Social Sciences (SPSS) and Comprehensive Meta-analysis (CMA-3). Results: We identified 2533 studies after database searching, and 55 were included in quantitative and narrative synthesis. All analyses were done in tertiary care settings in densely populated central parts of Nepal. Ischemic stroke was more frequent (70.87%) than hemorrhagic (26.79%), and the mean age of stroke patients was 62,9 years. Mortality occurred in 16.9% (13-21.7%), thrombolysis was performed in 2.39% of patients, and no studies described thrombectomy or stroke unit care. Conclusion: The provision of stroke care in Nepal needs to catch up to international standards, and our systematic review demonstrated the need to improve access to quality stroke care. Dedicated studies on establishing stroke care units, prevention, rehabilitation, and studies on lower levels of care or remote regions are required. [ABSTRACT FROM AUTHOR]

Nepal experienced political change from absolute monarchy to constitutional monarchy in 1990 and finally to a republic in 2008. These changes in the political climate were followed by subsequent change in the educational policy as the incoming regimes tried to incorporate its ideology in the educational policy. This paper analyses the role of teachers' unions in the educational reform in Nepal since the 1990s with special focus on private schooling context. This paper draws information collected through qualitative interviews with teachers, administrators and principals of two private schools in Kathmandu, the capital city of Nepal. It also uses documentary sources including newspaper articles and other documents related to private schooling in general and teachers' unions in particular. This study found that teachers' unions in the context of private schools in Nepal are still struggling for survival due to lack of support from the stakeholders of private schools.

Background: Okhaldhunga is a hilly district with fragile socioeconomic conditions, limited access to health care, social stigma, and poor resource management, where most people rely on medicinal plants for primary health care. The use of medicinal plants for primary health care varies with socioeconomic attributes. Following the intra-cultural analysis, we documented and tested the hypothesis that use of medicinal plants in Champadevi, Okhaldhunga, Nepal, depends on socioeconomic variables. Methods: We interviewed 224 respondents, 53.12% female and 46.88% male, including 31 Brahmin, 157 Chhetri, 13 Dalit, and 23 Janajati, and conducted three focused group discussions and seven key informant interviews to record the ethnomedicinal plants used in Champadevi rural municipality, Okhaldhunga District. The relative frequency of citation (RFC) was computed to know the importance of the species. A generalized linear model (GLM) was used to see the relationship between medicinal plants reported with the sociocultural variables, which include age, gender, occupation, education, ethnicity, and religion. Results: We documented 149 medicinal plants, including 69 herbs, 22 shrubs, nine climbers, 48 trees, and one parasitic plant, belonging to 68 families and 130 genera, and used to treat 48 distinct diseases and ailments. Plant parts, leaf, and digestive disorders were frequently treated during healing. Curcuma angustifolia was the most cited species with RFC 0.9554. The respondents' knowledge of medicinal plant use varied significantly with age (p = 0.0001) and occupation (p = 0.003). Changes in land use, population decline of medicinal plant species, and unsustainable harvesting practices constituted the local threats to medicinal plants and associated knowledge. Elders died without passing on their knowledge to the younger generations during sociocultural transformation, and youth disinterest coupled with the free availability of allopathic medicine led to knowledge erosion. Conclusions: The use of medicinal plants in Champadevi, Okhaldhunga, was significantly depended on two socioeconomic variables age and occupation. Ethnomedicinal plants are essential in the primary healthcare system in Nepal; however, their availability and practices are declining. Thus, plans regulating land use change and human migration, acknowledging traditional healthcare practices, and raising awareness of the significance of traditional medical practices as complementary healthcare practices should be strengthened. [ABSTRACT FROM AUTHOR]

Coffee is an established plant for its flavor and has high commercial use. In Nepal, the popularity of coffee is increasing for its high economic value. However, its diversity and the status of its genetic mapping have not been studied in Nepal. In the present study, the genetic diversity of 28 coffee accessions was assessed by using twenty-four SSR markers with the aim of studying the variation of coffee in accord with the genetic markers from a molecular approach. With the use of DNA extraction and marker selection for its amplification using PCR tools, a total of 81 loci from SSR were identified. Of all SSR 63.22% showed for mean polymorphism. The mean polymorphic information content of SSR was 0.38, which showed low genetic diversity of SSR markers among Coffea genotypes. On the basis of the SSR marker, the unweighted pair group method with arithmetic mean (UPGMA) dendrogram constructed showed a similar group of distribution among 28 accessions, which was further supported by a principle coordinate analysis scatter plot. The phylogenetic relationships among the accessions were assessed by SSR marker, which also showed low diversity in coffee genotypes. Our study demonstrated the use of SSR markers in diversity analysis as the data were informative and highly reproducible for evaluating relationships among coffee cultivars in Nepal. The use of more markers systems and a high genotype pool would have been beneficial in accessing more accurately. Regardless, the information from the phylogenetic relationship study could be useful for breeding, varietal improvement, and for conservation programs. [ABSTRACT FROM AUTHOR]

In the past few decades, the Nepali government has endorsed several nutritional policies, strategies, and guidelines. Given the lack of a comprehensive review of such policy documents, this review aims to describe the nutrition and food security policies and understand the existing policy gaps in Nepal. Findings from this study can be used to develop policies and programs to address Nepal's current and future nutritional needs. Policies relevant to nutrition and food security were identified by searching government websites and directly approaching relevant government ministries. Thematic analysis was conducted using framework methods under 8 predetermined themes: nutrition intervention, food security, food system, capacity building of human resources, nutrition education, nutrition governance, research, and monitoring and evaluation. The contents of each document reviewed were manually extracted in a spreadsheet stratified by the themes, and the findings were summarized for the respective themes. A total of 30 policy documents were reviewed. Most policies have focused on undernutrition; only a few have addressed overnutrition and diet-related noncommunicable diseases. Food security through a sustainable food system has been considered a key policy area in Nepal. Other areas in the food and nutrition policy landscape are capacity building for human resources, behavior change practices, nutrition governance, monitoring, and evaluation. Policy gaps have been identified in the quality and sustainability of nutrition programs; access to health care services; competent human resources for nutrition; intersectoral coordination and commitment; and support for monitoring, evaluation, and research activities. Most policies have tried to address a wide range of components of food and nutrition security; however, strategies focused on overnutrition and diet-related noncommunicable diseases are lacking. Several gaps are identified in this policy review; the findings can guide the policymakers to address these gaps via further policy development. [ABSTRACT FROM AUTHOR]

This paper discusses experiences from school-based needs assessment within a Participatory Action Research (PAR) project aimed at facilitating quality education in public schools of rural Nepal. Being often a first stage in the process of research-action, Participatory Needs Assessment (PNA) offers space for community members' perceptions and attitudes toward their collective needs. In this light, this paper takes evidence from the first and the second authors' Ph.D. experiences, under the supervision of the third and the fourth authors to initiate PNA of a school. Also, incorporating the reflections from the fifth author as a critical friend, it observes the political, epistemological, ethical, and methodological challenges of doing such assessments; the challenges of involving all the stakeholders in identifying problems, and the transformative possibilities the approach inherently brings within it. On the whole, the paper reflects how, despite manifold conflicting interests of the multi-group stakeholders, relational ontology(ies) emerged in the cyclical and spiral process. [ABSTRACT FROM AUTHOR]

Introduction ATP-binding cassette transporter A1 (ABCA1) encoded by ABCA1 gene is one of the important protein involved in lipid metabolism. The effect of statin therapy on dyslipidemia varies among individuals and it may be due to different genetic polymorphism. The R219K polymorphism of ABCA1 gene is found to have a significant role in the response of statin. Objective This study was designed to evaluate the effect of R219K polymorphism in lipid-lowering action of statin in patients with dyslipidemia. Material and Methods This study was conducted in 88 patients. Blood samples were taken from patients before and at the end of 3 months of statin use and were analyzed for lipid profile. Whole blood was analyzed for R219K Polymorphism using polymerase chain reaction-restriction fragment length polymorphism. Results R219K polymorphism was associated with significant percentage reduction of serum triglyceride/high-density lipoprotein (TG/HDL) ratio and total cholesterol/high-density lipoprotein (TC/HDL) ratio in atorvastatin users. However, there was no significant association of polymorphism with change in serum TC, HDL-C, LDL-C, TG, and very low-density lipoprotein (VLDL). Among KK genotype individuals, value of TG, VLDL, TG/HDL, and TC/HDL were significantly lower than in RR genotypes. Also, TG/HDL and TC/HDL were significantly lower in RK genotype than in RR. Treatment of dyslipidemia with statin was found to be comparatively better in patients having the genotypes KK and RK. Conclusion Our study demonstrated association of R219K polymorphism with the significant reduction of TG/HDL and TC/HDL and particularly the KK genotype was associated with significant improvement of lipid parameters following atorvastatin treatment. [ABSTRACT FROM AUTHOR]

Horsegram (Macrotyloma uniflorum [Lam.] Verdc.) is an underutilized pulse crop primarily cultivated in South Asian countries like India, Nepal, and Sri Lanka. It offers various nutraceutical properties and demonstrates remarkable resilience to both biotic and abiotic stresses. As a result, it has emerged as a promising crop for ensuring future food and nutritional security. The purpose of this study was to assess the nutritional profile of 139 horsegram germplasm lines obtained from 16 Indian states that were conserved at the National Gene Bank of India. Standard analytical methods, including those provided by the Association of Official Analytical Chemists (AOAC), were used for this investigation. The study revealed substantial variability in essential nutrients, such as protein (ranging from 21.8 to 26.7 g/100 g), starch (ranging from 26.2 to 33.0 g/100 g), total soluble sugars (TSSs) (ranging from 0.86 to 12.1 g/100 g), phenolics (ranging from 3.38 to 11.3 mg gallic acid equivalents (GAEs)/g), and phytic acid content (ranging from 1.07 to 21.2 mg/g). Noteworthy correlations were observed, including a strong positive correlation between sugars and phenols (r = 0.70) and a moderate negative correlation between protein and starch (r = −0.61) among the studied germplasm lines. Principal component analysis (PCA) highlighted that the first three principal components contributed to 88.32% of the total variability, with TSSs, phytates, and phenols emerging as the most significant contributors. The cluster analysis grouped the accessions into five clusters, with cluster III containing the accessions with the most desirable traits. The differential distribution of the accessions from north India into clusters I and III suggested a potential geographical influence on the adaptation and selection of genes. This study identified a panel of promising accessions exhibiting multiple desirable traits. These specific accessions could significantly aid quality breeding programs or be directly released as cultivars if they perform well agronomically. [ABSTRACT FROM AUTHOR]

Background: Globally, the majority of strokes affect people residing in lower-and lower-middle-income countries (LMICs), but translating evidence-based knowledge into clinical practice in regions with limited healthcare resources remains challenging. As an LMIC in South Asia, stroke care has remained a healthcare problem previously unaddressed at a national scale in Nepal. The Nepal Stroke Project (NSP) aims to improve acute stroke care in the tertiary healthcare sector of Nepal. We hereby describe the methods applied and analyze the barriers and facilitators of the NSP after 18 months. Methods: The NSP follows a four-tier strategy: (1) quality improvement by training healthcare professionals in tertiary care centers; (2) implementation of in-hospital stroke surveillance and quality monitoring system; (3) raising public awareness of strokes; and (4) collaborating with political stakeholders to facilitate public funding for stroke care. We performed a qualitative, iterative analysis of observational data to analyze the output indicators and identify best practices. Results: Both offline and online initiatives were undertaken to address quality improvement and public awareness. More than 1,000 healthcare professionals across nine tertiary care hospitals attended 26 stroke-related workshops conducted by Nepalese and international stroke experts. Monthly webinars were organized, and chat groups were made for better networking and cross-institutional case sharing. Social media-based public awareness campaigns reached more than 3 million individuals. Moreover, live events and other mass media campaigns were instituted. For quality monitoring, the Registry of Stroke Care Quality (RES-Q) was introduced. Collaboration with stakeholders (both national and international) has been initiated. Discussion: We identified six actions thatmay support the development of tertiary care centers into essential stroke centers in a resource-limited setting. We believe that our experiences will contribute to the body of knowledge on translating evidence into practice in LMICs, although the impact of our resultsmust be verified with process indicators of stroke care. [ABSTRACT FROM AUTHOR]

Coffee is the most popular beverage containing numerous phytochemical components that have antioxidant activity capable of scavenging free radicals. Antioxidant and phenolic contents have considerable benefits for human health. The aim of this study was the molecular identification of 9 coffee samples from the Nepal Agricultural Research Council, Lalitpur, Nepal, and the determination of the antioxidant activity and total phenolic content of green and roasted coffee beans. Molecular identification was performed using ITS-specific PCR followed by sequencing and phylogenetic tree construction using the maximum parsimony method. The DPPH assay was used to determine the antioxidant activity, and the Folin–Ciocalteu (F-C) assay was used to determine the total phenolic content. All the samples belonged to the taxa Coffea arabica. The antioxidant activity in roasted beans varied from 2.49 to 4.62 AAE mg/g and from 1.4 to 3.9 AAE mg/g in green beans. The total phenolic content varied from 2.58 to 3.38 GAE mg/g and from 4.16 to 5.36 GAE mg/g for the roasted beans and green beans, respectively. The data revealed that the highest antioxidant content (4.62 AAE mg/g) was found in roasted coffee and that the highest phenolic content (5.36 GAE mg/g) was found in green coffee. The study concludes that roasting increases the antioxidant activity but decreases the phenolic content of coffee. [ABSTRACT FROM AUTHOR]

Background: Land use and land cover changes have a significant impact on the dynamics of soil organic matter (SOM) and its fractions, as well as on overall soil health. This study conducted in Bharatpur Catchment, Chitwan District, Nepal, aimed to assess and quantify variations in total soil organic matter (TSOMC), labile organic matter fraction (CL), stable organic matter fraction (CS), stability ratio (SR), and carbon management index (CMI) across seven land use types: pastureland, forestland, fruit orchards, small-scale conventional agricultural land, large-scale conventional agricultural land, large-scale alternative fallow and conventional agricultural land, and organic farming agricultural land. The study also explored the potential use of the Carbon Management Index (CMI) and stability ratio (SR) as indicators of soil degradation or improvement in response to land use changes. Results: The findings revealed significant differences in mean values of TSOMC, CL, and CS among the different land use types. Forestland and organic farming exhibited significantly higher TSOMC (3.24%, 3.12%) compared to fruit orchard lands (2.62%), small scale conventional farming (2.22%), alternative fallow and conventional farming (2.06%), large scale conventional farming (1.84%) and pastureland (1.20%). Organic farming and Forestland also had significantly higher CL (1.85%, 1.84%) and CS (1.27%, 1.39%) compared to all other land use types. Forest and organic farming lands showed higher CMI values, while pastures and forests exhibited higher SR values compared to the rest of the land use types. Conclusions: This study highlights the influence of various land use types on soil organic matter pools and demonstrates the potential of CMI and SR as indicators for assessing soil degradation or improvement in response to land use and land cover changes. [ABSTRACT FROM AUTHOR]

Despite the evidence of the disproportionate burden of tobacco use among people with HIV (PWH), little effort has been made to design and test smoking cessation interventions for PWH in resource-limited countries. We assessed the feasibility, acceptability, and preliminary effects of a video-based smoking cessation intervention consisting of eleven 3-8-minute sessions among PWH in Nepal, a lower-middle-income country. Guided by the phased-based model, our 3-month intervention focused on setting the quit date, smoking cessation, and abstinence maintenance. We screened 103 PWH over three weeks for our single-arm trial, with 53 considered eligible and 48 recruited (91%). Forty-six participants watched all video clips, while two watched 7–9. All participants were retained at a 3-month follow-up. The 1-week point prevalence abstinence (self-report supported with expired carbon monoxide levels < 5ppm) at 3-month follow-up was 39.6%. Most (90%) participants reported "very much" or "much" comfort with watching the videos on their smartphones, and all would recommend the intervention to other PWH who smoke. Overall, our pilot trial demonstrated the feasibility, acceptability, and high-level efficacy of the video-based smoking cessation intervention highlighting its potential for scaling up in Nepal and other resource-limited countries. [ABSTRACT FROM AUTHOR]

The problem of culturally decontextualised mathematics education faced by Nepali students, teachers and teacher educators has often been oriented by the view of the nature of "mathematics as a body of pure knowledge," which gives rise to an exclusive emphasis on an ideology of singularity, epistemology of objectivism, language of universality and logic of certainty whilst developing curriculum, conceiving pedagogies and implementing assessment strategies in school mathematics education and mathematics teacher education programmes. With epistemic referents of dialectical logics and performative imagination, an alternative view of the nature of "mathematics as an impure knowledge" is discussed with its possible disempowering features, such as essentialism, hegemony and dualisms. Finally, an inclusive view of the nature of "mathematics as im/pure knowledge system" is articulated with the help of various forms of dialectics.

Background: Stroke is a major global health problem and was the second leading cause of death worldwide in 2020. However, the lack of public stroke awareness especially in low- and middle-income countries (LMICs) such as Nepal severely hinders the effective provision of stroke care. Efficient and cost-effective strategies to raise stroke awareness in LMICs are still lacking. This study aims to (a) explore the feasibility of a social media-based stroke awareness campaign in Nepal using a cost-benefit analysis and (b) identify best practices for social media health education campaigns. Methods: We performed a stroke awareness campaign over a period of 6 months as part of a Stroke Project in Nepal on four social media platforms (Facebook, Instagram, Twitter, TikTok) with organic traffic and paid advertisements. Adapted material based on the World Stroke Day Campaign and specifically created videos for TikTok were used. Performance of the campaign was analyzed with established quantitative social media metrics (impressions, reach, engagement, costs). Results: Campaign posts were displayed 7.5 million times to users in Nepal. 2.5 million individual social media users in Nepal were exposed to the campaign on average three times, which equals 8.6% of Nepal's total population. Of those, 250,000 users actively engaged with the posts. Paid advertisement on Facebook and Instagram proved to be more effective in terms of reach and cost than organic traffic. The total campaign cost was low with a "Cost to reach 1,000 users" of 0.24 EUR and a "Cost Per Click" of 0.01 EUR. Discussion: Social media-based campaigns using paid advertisement provide a feasible and, compared to classical mass medias, a very cost-effective approach to inform large parts of the population about stroke awareness in LMICs. Future research needs to further analyze the impact of social media campaigns on stroke knowledge. [ABSTRACT FROM AUTHOR]