1. Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study.
- Author
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Mesker DJ, Poels MM, Ikram MA, Vernooij MW, Hofman A, Vrooman HA, van der Lugt A, and Breteler MM
- Subjects
- Aged, Aged, 80 and over, Cerebral Amyloid Angiopathy epidemiology, Cerebral Hemorrhage epidemiology, Female, Humans, Magnetic Resonance Imaging, Male, Microcirculation, Middle Aged, Netherlands epidemiology, Organ Size, Temporal Lobe blood supply, Cerebral Amyloid Angiopathy complications, Cerebral Amyloid Angiopathy diagnosis, Cerebral Cortex blood supply, Cerebral Hemorrhage complications, Cerebral Hemorrhage diagnosis
- Abstract
Objective: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds., Design: Population-based, cross-sectional analysis., Setting: The Rotterdam Scan Study., Participants: A total of 198 persons (age range, 61-95 years) with lobar microbleeds., Main Outcome Measures: Distribution of microbleeds over different lobes., Results: We found that lobar cerebral microbleeds occurred significantly more often in the temporal lobe, a region known to be more affected in cerebral amyloid angiopathy., Conclusion: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.
- Published
- 2011
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