1. The Relationship Between Grey-Matter and ASD and ADHD Traits in Typical Adults.
- Author
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Geurts, Hilde, Ridderinkhof, K., and Scholte, H.
- Subjects
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BRAIN physiology , *HIPPOCAMPUS physiology , *PARIETAL lobe , *THALAMUS physiology , *MAGNETIC resonance imaging , *ATTENTION-deficit hyperactivity disorder , *AUTISM , *QUESTIONNAIRES , *STATISTICS , *DATA analysis , *DISABILITIES , *PHYSIOLOGY - Abstract
We tested whether in 85 healthy adults (18-29 years) there is a relationship between grey-matter (GM) volume and autism and ADHD symptom severity. The structural MRI findings and autism and ADHD self-reports revealed that autism and ADHD symptom severity was correlated with GM volume in the left inferior frontal gyrus. Autism symptom-severity was correlated with the left posterior cingulate, ADHD with the right parietal lobe, right temporal frontal cortex, bilateral thalamus, and left hippocampus/amygdala complex. Symptom severity of both disorders form a continuum extending into the general population, but it seems to be an oversimplification to typify psychiatric disorders such as autism and ADHD solely as extremes of brain structure abnormalities. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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