1. Disturbances of dental development distinguish patients with oligodontia-ectodermal dysplasia from isolated oligodontia.
- Author
-
Dhamo, B., Kuijpers, M. A. R., Balk-Leurs, I., Boxum, C., Wolvius, E. B., and Ongkosuwito, E. M.
- Subjects
DENTITION ,TEETH abnormalities ,DENTAL pathology ,ORTHOPEDICS ,INCISORS ,DENTAL care ,ECTODERMAL dysplasia ,COMPARATIVE studies ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,PHENOTYPES ,EVALUATION research ,HYPODONTIA - Abstract
Objective: To investigate phenotypic differences in dental development between isolated oligodontia and oligodontia-ectodermal dysplasia (ED).Setting and Sample Population: A total of 129 patients diagnosed with isolated oligodontia and 22 patients with oligodontia as part of ED were eligible.Methods: The phenotype of dental development was assessed for the frequency of missing a certain tooth, dental age, development of each tooth present, abnormal size and abnormal shape of teeth. The data were analysed building linear, ordinal and logistic regression models.Results: Compared to patients with isolated oligodontia, patients with oligodontia-ED missed more frequently central incisors and second molars in both jaws, and lateral incisors in the mandible (P < .05). Oligodontia-ED was associated with delayed development of the permanent dentition (β = -0.10; 95% CI: -0.17, -0.03). Specifically, the maxillary teeth: right central incisor, right lateral incisor, right second premolar and left second premolar were delayed approximately from 2 to 4 developmental stages. In addition, the left mandibular second premolar was 3 developmental stages delayed. Abnormal shape of teeth was 7 times more evident in patients with oligodontia-ED compared to patients with isolated oligodontia (OR = 6.54; 95% CI: 2.34, 18.28). The abnormal size of teeth was not a distinctive characteristic for oligodontia-ED.Conclusions: Oligodontia-ED distinguishes from isolated oligodontia by more disturbances in dental development. The abnormal shape of incisors and canines in a patient with oligodontia can raise suspicions for accompanying ectodermal abnormalities. [ABSTRACT FROM AUTHOR]- Published
- 2018
- Full Text
- View/download PDF