1. Identification of Carbapenem-Resistant Klebsiella pneumoniaeHarboring KPC Enzymes in New Jersey.
- Author
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Tom Chiang, Noriel Mariano, Carl Urban, Rita Colon-Urban, Louise Grenner, Robert H.K. Eng, David Huang, Hema Dholakia, and James J. Rahal
- Subjects
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DRUG resistance in microorganisms , *KLEBSIELLA pneumoniae , *EPIDEMIOLOGY - Abstract
Klebsiella pneumoniaeisolates harboring KPC enzymes have been identified in many geographical areas since 2001. Numerous problems exist in the detection and treatment of patients with such isolates. The clinical characteristics and molecular epidemiology associated with 12 randomly chosen patients in whom these enzymes were detected by molecular methods are described. This is the first description of the identification of carbapenem-resistant K. pneumoniaeisolates harboring KPC β-lactamases at the Veterans Administration Hospital in New Jersey (VA NJHCS). Because recognition of carbapenem resistance in K. pneumoniaedue to KPC enzymes can only be achieved by molecular methods, detection in the Clinical Microbiology Laboratory by routine methods will continue to be difficult, leading to dilemmas in treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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