1. DSM-5 substance use disorder symptom clusters and HIV antiretroviral therapy (ART) adherence.
- Author
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Paschen-Wolff, Margaret M., Campbell, Aimee N.C., Tross, Susan, Choo, Tse-Hwei, Pavlicova, Martina, and Jarlais, Don Des
- Subjects
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CLINICAL drug trials , *ALCOHOLISM , *CANNABIS (Genus) , *HIV infections , *CLASSIFICATION of mental disorders , *NARCOTICS , *PATIENT compliance , *SOCIAL control , *SUBSTANCE abuse , *ANTIRETROVIRAL agents , *HARM reduction , *SYMPTOMS - Abstract
This study examines self-reported 30-day antiretroviral therapy (ART) adherence among 101 people living with HIV and substance use disorders (SUD) in New York City in terms of Diagnostic and Statistical Manual – 5th Edition (DSM-5) SUD symptom clusters: impaired control, social impairment, risky use and pharmacological criteria. Overall, 60.4% met DSM-5 criteria for stimulant, 55.5% for alcohol, 34.7% for cannabis and 25.7% for opioid SUD. Of the 76 participants with a current ART prescription, 75.3% reported at least 90% 30-day adherence. Participants with vs. without alcohol SUD were significantly less likely to report ART adherence (64.3% vs. 88.2%, p =.017). Endorsement of social impairment significantly differed among adherent vs. non-adherent participants with alcohol SUDs (74.1% vs. 100%, p =.038) and with opioid SUDs (94.1% vs. 50.0%, p =.040). Understanding specific SUD symptom clusters may assist providers and patients in developing strategies to improve ART adherence. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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