1. Membrane protein serendipity.
- Author
-
von Heijne G
- Subjects
- Animals, History, 20th Century, History, 21st Century, Humans, Lipid Bilayers chemistry, Lipid Bilayers metabolism, Membrane Proteins chemistry, Membrane Proteins genetics, Membrane Proteins metabolism, New York City, Protein Folding, Protein Sorting Signals, Signal Transduction, Sweden, Chemical Engineering history, Computational Biology history, Membrane Proteins history, Models, Molecular, Molecular Biology history, Physics history
- Abstract
My scientific career has taken me from chemistry, via theoretical physics and bioinformatics, to molecular biology and even structural biology. Along the way, serendipity led me to work on problems such as the identification of signal peptides that direct protein trafficking, membrane protein biogenesis, and cotranslational protein folding. I've had some great collaborations that came about because of a stray conversation or from following up on an interesting paper. And I've had the good fortune to be asked to sit on the Nobel Committee for Chemistry, where I am constantly reminded of the amazing pace and often intricate history of scientific discovery. Could I have planned this? No way! I just went with the flow …., Competing Interests: The author declares that he has no conflicts of interest with the contents of this article., (© 2018 von Heijne.)
- Published
- 2018
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