1. S78SCHIZOPHRENIA GWAS OF YORUBAS IN SOUTHWESTERN NIGERIA.
- Author
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Okewole, Adeniran, Oluwaranti, Oluwaseun, Adeniji, Adetayo, Awhangansi, Sewanu, Dade-Matthews, Adefunke, Awolaran, Dorcas, Sodiya, Olusegun, Daramola, Emmanuel, Dabiri, Idowu, Akingunola, Olumuyiwa, Owoeye, Isaiah, Omirin, Taiwo, Panagiotaropoulou, Georgia, Braun, Alice, and Ripke, Stephan
- Subjects
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YORUBA (African people) - Abstract
B Background: b In the past decade, genome wide association studies (GWAS) have yielded an upsurge in discovery of genetic variants associated with schizophrenia, which promises to revolutionise our understanding of the illness and our therapeutic arsenal. It has become increasingly recognised that while Africa is a rich source of genetic diversity, there has hitherto been a paucity of studies of genome wide association studies for schizophrenia. We used the most recent GWAS summary statistics of the Psychiatric Genomics Consortium (PGC) as training data to construct polygenic risk scores (PRS) and perform a replication experiment. [Extracted from the article]
- Published
- 2019
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