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This study presents the findings of a comprehensive geotechnical and seismic site investigation conducted at Otuasega Town located in Bayelsa State within the Niger Delta region of Nigeria. Subsurface exploration involved advancing 10 boreholes to 30 m depth using hollow stem auger drilling. Continuous disturbed and undisturbed soil sampling was performed at 1.5 m intervals for detailed geotechnical testing. Laboratory tests on the recovered soil samples established the index properties, classification, densities and consistency limits of the stratified deposits. The subsurface profile comprised alternating layers of clay, silt and sand typical of deltaic sediments, with the clay fractions exhibiting medium to high plasticity. Shear wave velocity (Vs) profiling using Multichannel Analysis of Surface Waves (WASW) techniques categorised the site predominantly as Site Class C and D based on international standards. The Standard Penetration Test (SPT) N-values ranged from 5 to 10, indicating soft normally consolidated clay conditions typical of the Niger Delta region. Predictive empirical models developed from the field and lab data showed strong correlations for estimating key geotechnical parameters such as SPT blow count, Vs and liquefaction resistance. Ground response analyses using the Vs and SPT data indicated significant site amplification potential, with peak ground accelerations up to 1.5 times the bedrock motion. Liquefaction analysis based on the empirical SPT-based methods revealed a high potential for liquefaction in the sandy layers, especially under strong earthquake shaking. The study characterized the complex sedimentology and provided baseline information for seismic microzonation and site-specific ground response analyses to advance understanding of geohazards in this delta environment. [ABSTRACT FROM AUTHOR]