1. Yaws, Haemophilus ducreyi, and Other Bacterial Causes of Cutaneous Ulcer Disease in the South Pacific Islands.
- Author
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G-Beiras C, Ubals M, Corbacho-Monné M, Vall-Mayans M, and Mitjà O
- Subjects
- Bacillaceae, Bacteroides, Bacteroides Infections diagnosis, Bacteroides Infections drug therapy, Bacteroides Infections epidemiology, Coinfection diagnosis, Coinfection drug therapy, Coinfection epidemiology, Coinfection microbiology, Fusobacterium, Fusobacterium Infections diagnosis, Fusobacterium Infections drug therapy, Fusobacterium Infections epidemiology, Haemophilus ducreyi, Humans, Pacific Islands epidemiology, Sanitation, Treponema, Treponema pallidum, Treponemal Infections diagnosis, Treponemal Infections drug therapy, Treponemal Infections epidemiology, Anti-Bacterial Agents therapeutic use, Chancroid diagnosis, Chancroid drug therapy, Chancroid epidemiology, Neglected Diseases, Skin Diseases, Bacterial diagnosis, Skin Diseases, Bacterial drug therapy, Skin Diseases, Bacterial epidemiology, Skin Diseases, Bacterial microbiology, Skin Ulcer diagnosis, Skin Ulcer drug therapy, Skin Ulcer epidemiology, Skin Ulcer microbiology, Yaws diagnosis, Yaws drug therapy, Yaws epidemiology
- Abstract
Cutaneous ulcers in the tropics are a painful and debilitating condition that anchors people into poverty. In rural regions of the South Pacific, infectious cutaneous ulcers are caused mainly by bacteria, including Treponema pallidum pertenue (yaws), Haemophilus ducreyi, and polymicrobial ulcers. For this group of infections the term cutaneous ulcer disease (CUD) is proposed. Some infections can cause malformations on the bone that have a permanent impact on lives in endemic communities. Better characterization of CUD may help design diagnostic tools and more effective antimicrobial therapies. This review updates the knowledge of CUD and discusses optimized terminology and syndromic management., Competing Interests: Disclosure Maria Ubals holds a Río Ortega Scholarship for PhD students., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2021
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