1. The Geographic Distribution, Venom Components, Pathology and Treatments of Stonefish ( Synanceia spp.) Venom.
- Author
-
Saggiomo SL, Firth C, Wilson DT, Seymour J, Miles JJ, and Wong Y
- Subjects
- Animals, Bites and Stings complications, Cardiovascular Diseases epidemiology, Cardiovascular Diseases etiology, Cardiovascular Diseases therapy, Fish Venoms analysis, Fish Venoms chemistry, Geography, Humans, Indian Ocean epidemiology, Neuromuscular Diseases epidemiology, Neuromuscular Diseases etiology, Neuromuscular Diseases therapy, Pacific Ocean epidemiology, Bites and Stings epidemiology, Bites and Stings therapy, Fish Venoms poisoning, Fishes, Poisonous physiology
- Abstract
Stonefish are regarded as one of the most venomous fish in the world. Research on stonefish venom has chiefly focused on the in vitro and in vivo neurological, cardiovascular, cytotoxic and nociceptive effects of the venom. The last literature review on stonefish venom was published over a decade ago, and much has changed in the field since. In this review, we have generated a global map of the current distribution of all stonefish ( Synanceia ) species, presented a table of clinical case reports and provided up-to-date information about the development of polyspecific stonefish antivenom. We have also presented an overview of recent advancements in the biomolecular composition of stonefish venom, including the analysis of transcriptomic and proteomic data from Synanceia horrida venom gland. Moreover, this review highlights the need for further research on the composition and properties of stonefish venom, which may reveal novel molecules for drug discovery, development or other novel physiological uses.
- Published
- 2021
- Full Text
- View/download PDF