1. Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan.
- Author
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Ejaz H, Wang N, Wilksch JJ, Page AJ, Cao H, Gujaran S, Keane JA, Lithgow T, Ul-Haq I, Dougan G, Strugnell RA, and Heinz E
- Subjects
- Adolescent, Anti-Bacterial Agents pharmacology, Child, Child, Hospitalized, Child, Preschool, Humans, Infant, Infant, Newborn, Klebsiella Infections epidemiology, Klebsiella pneumoniae isolation & purification, Pakistan epidemiology, Phylogeny, Sequence Analysis, DNA, Drug Resistance, Multiple, Bacterial genetics, Genome, Bacterial genetics, Klebsiella Infections microbiology, Klebsiella pneumoniae genetics
- Abstract
Klebsiella pneumoniae shows increasing emergence of multidrug-resistant lineages, including strains resistant to all available antimicrobial drugs. We conducted whole-genome sequencing of 178 highly drug-resistant isolates from a tertiary hospital in Lahore, Pakistan. Phylogenetic analyses to place these isolates into global context demonstrate the expansion of multiple independent lineages, including K. quasipneumoniae.
- Published
- 2017
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