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1. ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia-Brief Report.

Author

Reeskamp LF, Millar JS, Wu L, Jansen H, van Harskamp D, Schierbeek H, Gipe DA, Rader DJ, Dallinga-Thie GM, Hovingh GK, and Cuchel M

Subjects
Adult, Angiopoietin-Like Protein 3, Angiopoietin-like Proteins metabolism, Antibodies, Monoclonal adverse effects, Anticholesteremic Agents adverse effects, Biomarkers blood, Female, Genetic Predisposition to Disease, Homozygote, Humans, Hyperlipoproteinemia Type II blood, Hyperlipoproteinemia Type II diagnosis, Hyperlipoproteinemia Type II genetics, Liver metabolism, Male, Mutation, Netherlands, Pennsylvania, Phenotype, Receptors, LDL genetics, Receptors, LDL metabolism, Time Factors, Treatment Outcome, Angiopoietin-like Proteins antagonists & inhibitors, Antibodies, Monoclonal therapeutic use, Anticholesteremic Agents therapeutic use, Apolipoprotein B-100 blood, Cholesterol, LDL blood, Hyperlipoproteinemia Type II drug therapy, Lipoproteins, IDL blood, Lipoproteins, LDL blood, Liver drug effects
Abstract

[Figure: see text].

Published
2021
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