1. Percutaneous cardiac assist devices compared with surgical hemodynamic support alternatives: cost-effectiveness in the emergent setting.
- Author
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Maini B, Gregory D, Scotti DJ, and Buyantseva L
- Subjects
- Cardiac Catheterization adverse effects, Cardiac Catheterization instrumentation, Cardiac Catheterization mortality, Cost-Benefit Analysis, Hospital Costs, Humans, Length of Stay economics, Models, Economic, Myocardial Infarction complications, Myocardial Infarction diagnosis, Myocardial Infarction mortality, Myocardial Infarction physiopathology, Patient Discharge economics, Pennsylvania, Prosthesis Design, Prosthesis Implantation adverse effects, Prosthesis Implantation instrumentation, Prosthesis Implantation methods, Prosthesis Implantation mortality, Quality-Adjusted Life Years, Retrospective Studies, Shock, Cardiogenic diagnosis, Shock, Cardiogenic etiology, Shock, Cardiogenic mortality, Shock, Cardiogenic physiopathology, Time Factors, Treatment Outcome, Cardiac Catheterization economics, Cardiology Service, Hospital economics, Emergency Service, Hospital economics, Heart-Assist Devices economics, Hemodynamics, Myocardial Infarction economics, Myocardial Infarction therapy, Prosthesis Implantation economics, Shock, Cardiogenic economics, Shock, Cardiogenic therapy
- Abstract
Unlabelled: This study evaluates the cost-effectiveness of percutaneous cardiac assist device (pVAD) therapy in the emergent setting compared with traditional surgical hemodynamic support alternatives., Background: Previous research has demonstrated the cost-effectiveness of pVAD hemodynamic support for patients undergoing high-risk percutaneous coronary intervention. For patients in cardiogenic shock (CS), use of pVAD therapy has been shown to reduce length of stay (LOS)., Methods: National utilization and outcome data from the 2010-2011 MedPAR and state-sponsored all-payer databases were collected for patients with an acute myocardial infarction complicated by CS who were treated with either a pVAD (n = 883) or with traditional surgical hemodynamic support alternatives (ECMO and extracorporeal VAD) (n = 305)., Results: Discharge survival was greater with pVADs than with surgical alternatives (56% vs. 42%, P < 0.001) and was achieved with a strong trend toward reduced LOS (13.2 and 17.9 days, respectively, P = 0.055) and a significantly lower cost of the index admission ($90,929 and $144,257, respectively, P < 0.001). Cost-effectiveness analysis based on the national data demonstrated that pVAD achieved improved outcomes at lower cost. Data were also collected for similar patients who underwent protocol-guided pVAD therapy (using Impella 2.5) at PinnacleHealth, between 2009 and 2011 (n = 30). At this site, the survival rate increased to 60%, length of hospitalization was shortened to 6 days, and admission costs were lowered to $53,850 relative to the surgical alternatives strategy., Conclusions: For patients in CS requiring emergent hemodynamic support, pVAD therapy offers a less invasive alternative that can be deployed sooner, resulting in better outcomes, shorter LOS, lower costs and with no incremental cost, and a survival benefit when compared with traditional surgical hemodynamic support alternatives. PVAD therapy (and Impella 2.5 in particular) is emerging as a dominant strategy for this challenging patient population., (Copyright © 2013 Wiley Periodicals, Inc.)
- Published
- 2014
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