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1. Genetic polymorphisms of orosomucoid ORM1 and ORM2 in Egyptians, Sudanese, and Qataris: occurrence of two new alleles.

Author

Sebetan IM, Oshida S, Yuasa I, and Tie J

Subjects
Alleles, Egypt, Gene Frequency, Humans, Phenotype, Qatar, Sudan, Orosomucoid genetics, Polymorphism, Genetic
Abstract

Isoelectric focusing was used to investigate the genetic variants of the human plasma orosomucoid ORM1 and ORM2 gene loci in samples of Egyptians, Sudanese, and Qataris. The study populations were classified into 28 ORM phenotypes determined by 10 ORM1 and 9 ORM2 alleles that included 2 new alleles, designated ORM1*B13 and ORM2*H21. Family studies of these new alleles are in accordance with codominant autosomal inheritance. A new interpretation for two previously reported alleles, ORM1*C6 and ORM2*H17, is also presented.

Published
1997

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