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Moose-vehicle collisions are a frequent traffic-safety issue, particularly in northern regions where moose are attracted to the near-road areas because they can consume sodium from de-icing salts that accumulate in pools at snowmelt. Moose that find salt pools near roads tend to remember their location and to re-visit them to get the sodium they need in their diet. This study investigated the trade-off between road avoidance and salt pool spatial memory in the movement behaviour of moose using an agent-based model to determine how the interplay of these two factors influences the frequency of road crossings in the Laurentides Wildlife Reserve (Québec, Canada). Mitigation measures studied were the removal of roadside salt pools and the construction of compensatory salt pools away from the road shoulder. A GPS telemetry program of moose in the study area was used to validate our model. The model moose with both road avoidance and salt pool spatial memory activated produced the best results when comparing to the real moose data. Results show that both road avoidance and salt pool spatial memory significantly affect moose road crossings, but that road avoidance explains most of the variance. Road avoidance tended to decrease the number of moose crossings, but this decrease was partly compensated by the spatial memory of salt pools which typically increased the likelihood that moose will cross the road. The trade-off between road avoidance and salt pool memory was largest when original salt pools were maintained. In simulations where road avoidance and salt pool memory were both turned off, the impact of mitigation measures on the number of road crossings was lowest. For the most realistic moose behavior, the management scenarios resulted in reductions in road crossings between 22% and 79%, and the best scenario is to completely remove roadside salt pools. If compensation salt pools are used, they should be located as far as possible from the roads (beyond 500m) to have an impact on moose road crossings. [Copyright &y& Elsevier]