1. Prevalence and histopathological types of skin carcinomas in Arges County, Romania.
- Author
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Tânţu MM, Belu E, Man GM, Manu D, Rogozea LM, Stocheci CM, Bălăşoiu AT, Stănescu C, and Domnariu CD
- Subjects
- Adult, Age Distribution, Aged, Aged, 80 and over, Carcinoma, Basal Cell epidemiology, Carcinoma, Basal Cell pathology, Carcinoma, Squamous Cell epidemiology, Carcinoma, Squamous Cell pathology, Cell Differentiation, Female, Humans, Male, Middle Aged, Prevalence, Romania epidemiology, Young Adult, Skin Neoplasms epidemiology, Skin Neoplasms pathology
- Abstract
Non-melanoma skin cancers presented a significant incidence increase in the last decades, worldwidely. Even though the impact upon mortality is a relatively low one, through the incidence increase, their impact upon the public healthcare systems is a considerable one. In our study, we evaluated 109 cases of skin carcinomas hospitalized during 2012 in the Department of Plastic Surgery of the Emergency Hospital of Pitesti, Romania, for a surgical treatment. The gender distribution showed slight lesion predominance in women, being recorded 56 (51.38%) tumors in women and 53 (48.62%) in men. The highest incidence of skin carcinomas (75.23%) was recorded in the persons aged over 60-year-old. Of 109 cases of skin carcinomas, 80 (73.4%) carcinomas developed on indignant tegument areas, while 29 (26.6%) on premalignant skin lesions (fiberconjunctive papillomas, keratocantomas, keratosic verrucas). The histopathological study highlighted the fact that of 109 skin carcinomas, 87 (79.82%) were basal cell carcinomas and only 22 (20.18%) were squamous cell carcinomas. The immunohistochemical reaction to 34βE12 cytokeratin was highly positive in the cells of the basal cell carcinomas and well-differentiated squamous cell carcinomas (except for the "keratosic pearls") and moderately positive in the moderately differentiated squamous cell carcinoma.
- Published
- 2014