1. Nipple-sparing Mastectomy in Patients with Preoperative Diagnosis of Non-invasive Breast Carcinoma. A Single-center Experience.
- Author
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Amabile MI, Monti M, Merola R, Frusone F, D'Orazi V, and Pasta V
- Subjects
- Adult, Breast Implantation instrumentation, Breast Implants, Breast Neoplasms pathology, Carcinoma pathology, Female, Humans, Mastectomy adverse effects, Middle Aged, Neoplasm Invasiveness, Prosthesis Design, Retrospective Studies, Rome, Silicones, Time Factors, Tissue Expansion instrumentation, Tissue Expansion Devices, Treatment Outcome, Breast Neoplasms surgery, Carcinoma surgery, Mastectomy methods, Nipples surgery
- Abstract
Background: Nipple-sparing mastectomy (NSM) is a recognized treatment for selected patients with breast cancer (BC). Our study aimed to analyze 7 years' experience in NSM and breast reconstruction for patients with preoperative diagnosis of non-invasive BC., Patients and Methods: All NSMs with breast reconstruction, performed between January 2007 and December 2013 in patients with preoperative diagnosis of non-invasive BC, were considered., Results: Thirty-five NSMs were performed, 23 cases confirming the diagnosis of non-invasive BC, and in 12 patients it also resulted in findings of an invasive component. Patients were stratified into two groups: breast reconstruction was performed i) with silicone definitive implant, ii) with a temporary breast tissue expander. An invasive component at the postoperative histological examination was significantly associated with tissue expander reconstruction (p=0.03)., Conclusion: In selected cases, NSM is a valid and safe procedure. Further critical evaluations are required for more evidence on this argument., (Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.)
- Published
- 2016