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Objective: To investigate the prevalence and risk factors of functional dyspepsia (FD) and irritable bowel syndrome (IBS) among college students in China., Methods: An online questionnaire survey of college students aged 17-35 from across China was conducted. The online questionnaire survey was supplemented by an offline survey. A total of 2025 valid samples were included for statistical analysis. χ 2 test and logistic regression were performed for statistical analysis., Results: The prevalence of FD among college students who met the Rome Ⅳ diagnostic criteria was 5.5% (112/2025), with most of them, or 66.1% (74/112), suffering from postprandial discomfort syndrome (PDS). Smoking (odds ratio [ OR ]=2.334, 95% confidence interval [ CI ]: 1.187-4.589, P =0.014), depression ( OR =2.447, 95% CI : 1.421-4.214, P =0.001), and insomnia ( OR =1.947, 95% CI : 1.291-2.937, P =0.001) were positively correlated with the prevalence of FD. The prevalence of IBS was 1.9% (38/2025), with IBS-diarrhea dominant (IBS-D) being the most important subtype that accounted for 44.7%. Anxiety ( OR =3.63, 95% CI : 1.34-9.88, P =0.012) and insomnia ( OR =2.35, 95% CI : 1.18-4.68, P =0.015) were positively correlated with the prevalence of IBS., Conclusion: Based on Rome Ⅳ criteria, IBS and FD are not uncommon among Chinese university students. Psychological disorders and some related lifestyle factors may be related to the development of the disease. In the future, more series of studies based on different diagnostic criteria, different regions, and multiple factors should be conducted in China., (Copyright© by Editorial Board of Journal of Sichuan University (Medical Sciences).)