A report from the Erasmus University Medical Center in Rotterdam, Netherlands, discusses the management and clinical outcomes of pregnancies in women with urea cycle disorders (UCDs). The research highlights the increased number of women with UCDs reaching child-bearing age and becoming pregnant, as well as the risks associated with pregnancy for these women. The study found that with multidisciplinary management and a prospective plan, successful pregnancies, labor, delivery, and postpartum periods can be achieved. However, there is limited follow-up data on the clinical outcomes of children born to mothers with UCDs. The research emphasizes the importance of early diagnosis and treatment to prevent complications and deaths in previously undiagnosed women. [Extracted from the article]