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1. [Population association features of interleukine gene polymorphism in khakases with gastroduodenal diseases].

Author

Ageeva ES, Shtygasheva OV, and Riazantseva NV

Subjects
Adolescent, Adult, Alleles, Duodenal Diseases blood, Duodenal Diseases ethnology, Female, Genotype, Humans, Interleukins blood, Male, Middle Aged, Polymerase Chain Reaction, Prevalence, Russia epidemiology, Stomach Diseases blood, Stomach Diseases ethnology, Young Adult, DNA genetics, Duodenal Diseases genetics, Ethnicity, Genetic Predisposition to Disease, Interleukins genetics, Polymorphism, Genetic, Stomach Diseases genetics
Abstract

Aim: To investigate association of polymorphisms of IL-1 genes and antagonist of IL-2 receptor (IL1Ra)., Material and Methods: Patients with chronic gastritis and ulcer were examined using the method of restriction analysis., Results: It was found that CCILbeta and R4/R4IL1Ra are most prevalent allel variants in khakas population., Conclusion: It is expedient to define population risk and protective genotypes of development of ulcer associated with Helicobacter pylori in khakases.

Published
2011

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