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It has been established as result of studies with the use of complex sanitary-hygienic, microbiological, clinical and statistical methods, that the increasing antropogenic stress causes changes in microbiocenosis of water objects of the environment and of blood serum, which may produce unfavourable human health effects. The necessity to use integral complex indexes of the state of man and water medium for the assessment of the degree of risk of ++eco-technogenic effects has been found out.

It has been found out as result of complex sanitary-hygienic, microbiological and statistical studies, that the intensity of processes of self-purification of the water in water objects form potentially pathogenic microflora is reduced under the im fluence of the increasing anthropogenic stress on the water bodies in the Southern area which can produce unfavourable human health effects. The necessity that a complex of sanitary-microbiological indicators of water quality should be used to provide its epidemic safety has been revealed, and also a criterion of the assessment of the process of self-purification of the water in water bodies according to the acute intestinal infections morbidity of the population.