1. An overview of experiments with lead-containing nanoparticles performed by the Ekaterinburg nanotoxicological research team.
- Author
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Minigaliyeva IA, Sutunkova MP, Gurvich VB, Bushueva TV, Klinova SV, Solovyeva SN, Chernyshov IN, Valamina IE, Shur VY, Shishkina EV, Makeyev OH, Panov VG, Privalova LI, and Katsnelson BA
- Subjects
- Animals, Cell Line, Fibroblasts drug effects, Humans, Materials Testing, Rats, Russia, Toxicity Tests, Copper toxicity, Lead toxicity, Metal Nanoparticles toxicity, Nanoparticles toxicity, Nanotechnology
- Abstract
Over the past few years, the Ekaterinburg (Russia) interdisciplinary nanotoxicological research team has carried out a series of investigations using different in vivo and in vitro experimental models in order to elucidate the cytotoxicity and organ-systemic and organism-level toxicity of lead-containing nanoparticles (NP) acting separately or in combinations with some other metallic NPs. The authors claim that their many-sided experience in this field is unique and that some of their important results have been obtained for the first time. This paper is an overview of the team's previous publications in different journals. It is suggested to be used as a compact scientific base for assessing health risks associated not only with the production and usage of engineered lead-containing NPs but also with their inevitable by-production as toxic air pollutants in the metallurgy of lead, copper or their alloys and in soldering operations.
- Published
- 2020
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