1. Effects of Eugenol on Haemoproteus columbae in domestic pigeons ( Columba livia domestica ) from Riyadh, Saudi Arabia.
- Author
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Metwally DM, Al-Talhi RA, Barakat IAH, and ElKhadragy MF
- Subjects
- Animals, Saudi Arabia, Bird Diseases drug therapy, Bird Diseases parasitology, Columbidae parasitology, Eugenol pharmacology, Haemosporida growth & development, Protozoan Infections, Animal drug therapy, Protozoan Infections, Animal parasitology
- Abstract
Eugenol was investigated for the treatment of Haemoproteus columbae ( H. columbae ) infected squabs (young domestic pigeons, Columba domestica ). Thirty naturally-infected squabs were divided into three groups of 10 each. One group was treated with Eugenol, while the positive and negative control groups were administered buparvaquone (Butalex®) and distilled water, respectively. The number of infected red blood cells (RBCs) was calculated in all groups before and after treatment at 4-day intervals for 16 days. The results showed a significant therapeutic effect of Eugenol, with a progressive decrease in the number of infected RBCs from 89.20 ± 2.11 before treatment to 0.90 ± 0.31 at the end of treatment ( P ≤0.05). Butalex® was able to suppress the number of infected RBCs from 93.70 ± 1.72 before treatment to 0.90 ± 0.35 at the end of the experiment ( P ≤0.05). Eugenol showed therapeutic effects against H. columbae and may be regarded as a candidate for further studies to develop new drugs against blood parasites, in both animals and humans., (© 2019 The Author(s).)
- Published
- 2019
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