1. Awareness and Impact of Non-pharmaceutical Interventions During Coronavirus Disease 2019 Pandemic in Renal Transplant Recipients.
- Author
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Monaco A, Manzia TM, Angelico R, Iaria G, Gazia C, Al Alawi Y, Fourtounas K, Tisone G, and Cacciola R
- Subjects
- Adult, COVID-19, Case-Control Studies, Coronavirus Infections immunology, Cross-Sectional Studies, Female, Humans, Incidence, Italy epidemiology, Living Donors statistics & numerical data, Male, Middle Aged, Pandemics, Pneumonia, Viral immunology, Postoperative Complications immunology, Postoperative Complications virology, Prevalence, SARS-CoV-2, Saudi Arabia epidemiology, Tissue and Organ Harvesting adverse effects, Tissue and Organ Procurement statistics & numerical data, Betacoronavirus immunology, Coronavirus Infections epidemiology, Immunocompromised Host immunology, Kidney Transplantation adverse effects, Pneumonia, Viral epidemiology, Postoperative Complications epidemiology
- Abstract
The concerns generated by coronavirus disease 2019 (COVID-19) pandemic are having profound impact on solid organ transplantation (SOT). Non-pharmaceutical interventions (NPI) are currently the only measures available to contain COVID-19 in the general population and in more vulnerable recipients of any organ transplant. In this cross-sectional case control study from a patient survey undertaken in 2 transplant centers (TxC) in the Kingdom of Saudi Arabia and Italy, we aimed to appraise awareness of the NPI implemented by respective these governments. We have also evaluated the impact of COVID-19 on our kidney transplant (KT) recipients and a control group of kidney living donors (KLD). In our series, there were zero cases of COVID-19 among 111 KT recipients and 70 KLD of the control group. Demography, transplant type, immunosuppression regimes, and, importantly, the different COVID-19 prevalence in the 2 regions of the TxC did not appear to influence incidence of COVID-19 in our KT recipients. The absence of COVID-19 cases in our series was unexpected. Our findings suggest that awareness of NPI is associated with a successful containment of COVID-19 in vulnerable, immunosuppressed KT recipients., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2020
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