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The current study aims to identify the impact of applying governance standards in improving the performance of health organizations through a case study of Riyadh hospitals in the Kingdom of Saudi Arabia. This study is a descriptive cross-sectional study using a questionnaire. The sample of the current study consisted of (357) employees in Riyadh hospitals in the Kingdom of Saudi Arabia. To achieve the study objective, the researcher designed an electronic questionnaire to measure the impact of applying governance standards in improving the performance of health organizations. The validity and reliability of the study tool were also verified. The results of the study concluded that there is a strong correlation between the principles and standards of governance and improving performance in health organizations, and a strong correlation between administrative leadership and the application of governance standards, as well as a strong correlation between administrative leadership's adoption of governance standards and improving the performance of organizations. This shows that Riyadh hospitals in the Kingdom of Saudi Arabia possess the components that allow for activating the possibility of applying governance standards and thus improving performance, which is positively reflected in improving the level of health care. [ABSTRACT FROM AUTHOR]

Background: Effective inter-professional collaboration is vital for optimizing healthcare outcomes. This study focuses on healthcare workers in the Jizan Region, Kingdom of Saudi Arabia (KSA), to evaluate their knowledge, attitudes, and challenges concerning inter-professional collaboration. Aim: The study aims to assess the current state of interprofessional collaboration among healthcare workers (HCWs) in the Jizan Region, KSA, with a focus on understanding their knowledge levels, attitudes, identifying potential barriers, and examining the relationships between knowledge, attitudes, and demographic factors. Method: A descriptive and quantitative cross-sectional research design was employed, involving multidisciplinary healthcare teams in selected Jizan Region hospitals. Data were collected through a questionnaire measuring knowledge and attitudes, and analyses were conducted using SPSS version 28. Findings and Results: The demographic profile of healthcare workers in Jizan, KSA, reveals a predominantly male workforce (90.6%) with diverse educational backgrounds, notably featuring a high percentage of Ph.D. holders (33.1%). Psychometrically validated scales indicate positive attitudes (M=44.40) and high knowledge levels (M=49.34) among participants, with positively skewed distributions. Healthcare professionals displayed overwhelmingly positive attitudes (207 out of 257) and high knowledge levels toward emphasizing a positive foundation for collaborative practices in the region. Conclusion: The study contributes valuable insights to the KSA healthcare context, indicating a positive foundation for inter-professional collaboration. Recommendations include tailored training programs and interventions addressing communication barriers. Limitations, such as the crosssectional nature of the study, should be considered in interpreting the results. [ABSTRACT FROM AUTHOR]

The biliary tract has been referred to as the‘Achilles heel’ of liver transplantation. The aim of this study was to document the frequency, clinical presentation and management of biliary complications after liver transplantation in the King Faisal Specialist Hospital and Research Center (KFSH&RC), Riyadh, Saudi Arabia.The liver transplant clinic at KFSH&RC has registered and followed 220 patients (150 male and 70 female patients; age 40.6 ± 18.6 years; pediatric 33, adult 187) during the period from 1987 to June 2003. A total of 235 transplants were carried out on these patients. Cadaveric liver transplants had been carried out on 202 patients, non-heart beating liver transplant in three patients, live donor liver transplants in 11 and split transplant in four. Biliary reconstruction was duct-to-duct anastomosis in 147 patients and Roux-en-Y in 73. Biliary complications were suspected on clinical and biochemical parameters and confirmed using imaging techniques.Forty patients (18.2%) developed 53 biliary complications. These included bile leak in 16, strictures in 25, calculi in eight, and sphincter of Oddi dysfunction and possible recurrence of primary sclerosing cholangitis in the donor duct in two patients each. Bile leaks were observed in the early postoperative period (median period 30 days, range 1–150 days, 95% confidence interval[CI] 8–51). Leakage occurred at the anastomotic site in 13 patients. Patients presented with bilious drainage (n = 6), abdominal pain at T-tube removal (n = 3), fever (n = 2), sepsis (n = 1), dyspnea (n = 1) and abnormal liver tests (n = 3). Eleven patients had intra-abdominal bilious collections. Two patients were treated conservatively, eight patients had ultrasound-guided aspiration of biloma, five had biliary stenting at endoscopic retrograde cholangiopancreatography and two patients needed surgery. There were four deaths, two of which were related to bile leak, one patient was left with permanent external biliary drainage and four patients had biliary strictures in the follow-up period. Biliary strictures occurred at a median period of 360 days (range 4–2900 days; 95% CI 50–670) after the transplant. Hepatic artery thrombosis caused biliary strictures in three, while 21 strictures were localized to the anastomotic site. Biliary strictures presented with elevated liver tests in five patients, progressive cholestasis in five, cholangitis (with septicemia in five) in 11, abdominal pain in two and acute pancreatitis in three patients. Repeat sessions of endoscopic or percutaneous dilatation and stenting (mean sessions 4.4/patient, range 3–7) were attempted in 20 patients to relieve strictures, with success in only nine patients. Seven patients had surgery. Four patients with biliary strictures died. Biliary calculi developed late in the follow-up period and had the appearance of biliary casts in five and sludge in three patients. Eleven (27.5%) patients with biliary disease died compared with 35 (19.4%) patients without biliary disease.Biliary complications occurred in 18.2% of patients after liver transplantation and included biliary leak and biliary strictures with or without calculi. Management involved a combination of endoscopic, radiologic and operative procedures. Biliary complications caused considerable morbidity and mortality in liver transplant patients.© 2004 Blackwell Publishing Asia Pty Ltd [ABSTRACT FROM AUTHOR]

Despite global initiatives to eliminate dog-mediated human rabies by 2030, the Arabian Peninsula faces challenges due to insufficient data. This review addresses the current rabies situation and knowledge gaps in the region and proposes One Health interventions. Employing a mixed-method approach combining scoping and systematic review, the study commenced with a Delphi discussion to identify knowledge gaps and set objectives. The literature search encompassed published articles and grey literature. The spatial and temporal distribution of rabies was analysed, alongside quantitative meta-analyses to assess prevalence. Rabies virus gene sequences from the NCBI database were examined for reservoir hosts and evolutionary patterns. The final Delphi discussion with experts focused on addressing knowledge gaps and formulating One Health interventions. The first reported human rabies case in this region occurred in Saudi Arabia in 1980. Yemen reported the highest number of cases (439), followed by Iraq (249), Saudi Arabia (91), Jordan (14), and Oman (9). Fox bites accounted for the most cases (47.4%), followed by dog (36.8%) and wild animal (15.8%) bites. The virus was detected in at least 21 animal species. Phylogenetic analysis detected a single strain with two clades, with foxes being the primary virus reservoir. However, the experts expressed scepticism about the accuracy of rabies reports in scientific literature. To achieve the 2030 goal of eliminating dog-mediated human rabies, a stepwise approach towards rabies elimination assessment is crucial in the region. Enhanced surveillance, awareness campaigns, and access to post exposure prophylaxis are essential to address the disease burden., (© The Author(s) 2025. Published by Oxford University Press on behalf of the European Public Health Association.)

Background: This study aimed to assess the knowledge about guidelines related to COVID-19 infection control procedures among dental health care professionals (DHCPs) in the Jazan region., Methods: A cross-sectional study involving DHCPs (dental students, interns, and dentists) of the Jazan region between January and March 2021. A questionnaire with 35 items was developed and circulated online among the DHCPs. The dimensionality of the questionnaire was assessed using exploratory factor analysis (EFA). The level of awareness (LOA) was compared across the genders, level of professional experience, and exposure to guidelines. Participants were considered to have high LOA when they responded to 26 or more items correctly., Results: A total of 363 DHCPs participated in the survey. The questionnaire was found to be valid and reliable. EFA revealed a distinct three-factor structure. Moreover, 61.2% of the respondents had high LOA related to COVID-19 infection prevention. Among those who had high LOA, dentists (65.5%) were relatively more than the students (62.5%) and interns (46.2%). Among the six guideline statements related explicitly to operative dentistry, more than 50% of the respondents were aware of 3 guideline statements, while less than 50% of the respondents were aware of the remaining statements., Conclusions: Most DHCP had a high LOA for general COVID-19 infection prevention and control guidelines. Dentists, males, and those who read the guidelines had higher LOA than their counterparts.

Introduction: Diabetes mellitus is a common disease worldwide. It is considered as the third leading cause of death, in the developed countries followed by heart diseases and cancer., Aim: The aim of this study was to assess the effectiveness of the aqueous fraction of R. mucronata and A. marina leaves grown in Saudi Arabia alone or in combination as antidiabetic agents and explore its effect on the antioxidants status., Methods: One hundred and twenty male Wistar albino rats were divided into 8 groups were utilized in this study. Streptozotocin (STZ) was utilized for induction of diabetes. The effects of daily oral administration of aqueous extract from the leaves of R. mucronata (400 mg/kg BW), A. marina (400 mg/kg BW) and the combination of both plant extracts for 6 weeks were evaluated on blood glucose, insulin, tissues' antioxidants as well as pancreatic immunohistochemistry in normal, (STZ)-induced diabetic rats., Results: Oral administration of the plants extracts significantly reduced (p ≤ 0.001) serum glucose, insulin and improved the antioxidants status in the liver compared to the untreated rats. Immunohistochemically, the pancreas of diabetic rats treated with R. mucronata revealed a few islets β-cells (2-3%/ HPF) with positive caspase-3., Conclusion: The extract of R. mucronata exhibited a promising antidiabetic, antioxidant and tissue enhancing effects compared with A. marina alone or in combination., Competing Interests: The authors declare no conflicts of interest., (© 2020 Obidallah Hamdan Ali Al-Jaghthmi, Isam ELDin Mohamed ELAmin Abu Zeid, Khalid Mohammed Saeed Al-Ghamdi, Hassan Mohammad Heba, Mahmoud Saeed Ahmad.)