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Objective: To understand the barriers to abortion in Shanghai during the COVID‐19 pandemic, and to compare pre‐abortion mental health status before and during the crisis. Methods: In this case–control study, two groups of women seeking abortion (age ≥18 years, pregnancy duration <98 days) were recruited from March to September, 2021 (n = 1070) and from February to April 2022 (n = 625). The evaluation included COVID‐19‐related abortion stress questions, the Symptom Checklist‐90 Revised questionnaire, the Pittsburgh Sleep Quality Index (PSQI), and the Family Environment Scale Chinese version. The researchers conducted interviews and collected questionnaires. Results: The median pregnancy duration at abortion among women during the pandemic was 65 days, compared with 51 days in the pre‐pandemic group (P < 0.001). Anxiety and depression symptoms increased during the crisis (P < 0.001). Sleep disturbances were more common. Higher PSQI scores were related to increased anxiety and depression symptoms. A more negative family climate was described during the pandemic. Conclusion: During the COVID‐19 pandemic, abortion access was delayed and pre‐abortion mental disorders increased. More attention should be paid to the mental health of women seeking abortions, and innovations should be promoted to ensure abortion services without delay. Synopsis: Abortion access was delayed and risk of pre‐abortion mental disorders among women with unintended pregnancies was increased during the COVID‐19 pandemic in Shanghai. [ABSTRACT FROM AUTHOR]

The study was aimed to analyze the prevalence characteristics of non‐16/18 high‐risk human papillomaviruses (HR‐HPV) and the related risks for cervical abnormalities in south Shanghai. A total of 2291 HPV women who had been referred for a colposcopy due to HPV infection from @@@@@2016.12 to 2019.6 were enrolled. Combined with liquid‐based thin‐layer cell test (TCT) and pathological results of cervical biopsy, the infection spectrum and pathogenic risk of non‐16/18 HR‐HPV in local population were investigated. The results showed that the single HR‐HPV infection rate was significantly higher than that of multiple infection, and the five most frequently detected types were HPV16, HPV52, HPV18, HPV53, HPV58 in the group. The total proportion of non‐16/18 HR‐HPV infection was 68.22%, more than twice of HPV16/18. In cases with high‐grade cervical intraepithelial lesions (HSIL) or cervical cancer, non‐16/18 HR‐HPV infections account for 50.84% (single infection: 28.57%, multiple infection: 22.27%). The risk of cervical abnormalities caused by single HPV infection was ranked as HPV16 > HPV52 > HPV18 = HPV58 > HPV51 > HPV53 = HPV56 > others. Notably, among non‐16/18 HR‐HPV infected patients with HSIL/cancer lesions, the omission diagnostic rate of TCT was 62.81%. The infection rate of non‐16/18 HR‐HPV in whole study population was much higher than that of 16/18 type, and the infection rate of the former was also slightly higher in patients with HSIL and cancer. Due to the high omission diagnostic rate of TCT, we suggest patients with persistent non‐16/18 HPV infection should undergo colposcopy biopsy to reduce missed detection of HSIL and cancers. Highlights: •The five most dominant HPV genotypes were HPV16, HPV52, HPV18, HPV53, and HPV58.•The risk of cervical lesions caused by single HPV infection was ranked as: HPV16 > HPV52 > HPV18 = HPV58 > HPV51 > HPV53 = HPV56 > others.•The proportion of non‐16/18 HR‐HPV infection was more than twice the infection rate of HPV16/18. [ABSTRACT FROM AUTHOR]

Purpose: This study aimed to compare the bone mineral density (BMD) of older women living in rural and urban areas, and evaluate the potential factors affecting the risk of osteoporosis.Methods: We recruited 574 women aged 65 years or older from rural areas and 496 from urban areas in Shanghai, China. The BMD values of the lumbar vertebrae and total left hip were measured by a dual energy X-ray absorptiometry densitometer. We also recorded information about education level, family income, medications, reproductive and menstrual history, diet, smoking, and alcohol consumption.Results: Women in urban areas had significantly higher BMD in their lumbar spine, and there was a dramatic increase in the proportion of women with osteoporosis in rural areas. The age at menarche was significantly higher among women living in rural areas, and there were more years from menarche to menopause among urban women. Rural women had significantly higher numbers of both pregnancies and parity, and a significantly lower age at first parity. In multiple linear regression analyses, years from menarche to menopause was independently related to high lumbar spine BMD, while age at menarche and parity was independently related to low lumbar spine BMD.Conclusion: More older women in rural areas had osteoporosis. Later menarche, less years from menarche to menopause and higher parity might partially contribute to decreased BMD among women in rural areas. More attention should be paid to women in rural areas to prevent bone loss and further bone and health impairment. [ABSTRACT FROM AUTHOR]