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Taking the waste high-moisture slurry produced at a construction site in Shanghai as the research object, the pressure filtration effect of the slurry under the condition of agent conditioning was studied. First of all, the geotechnical characteristics of the waste slurry under agent conditioning were studied through laboratory experiments, and the selection and addition amount of the agent were preliminarily determined. Then, the influence of agent addition, stirring time, and pressure filtration time on the pressure filtration efficiency was studied through field experiments. Finally, a method to guide the field filtration time by the indoor model test was put forward. [ABSTRACT FROM AUTHOR]

Purpose: An isocentric rotating chair for a positioner was developed as a nongantry solution to provide multiple nonplanar radiation fields with a maximum tilt of 20∘ for treating head and neck cancer patients at an upright seated position in a fixed carbon‐ion beamline. Methods: The preclinical validation of the chair was present for this study funded by a grant through the Shanghai Proton and Heavy Ion Center (SPHIC) in Shanghai, China. The chair was installed in SPHIC. A concept of parallel kinematic was adopted to build the chair. Three movement subunits of the chair are a Stewart hexapod platform and two modules for three‐dimensional translation and 360∘ rotation. This chair can position patients with a tilt up to 20∘ over a continuous 360∘ rotation. Any weak structures within each subunit were investigated by industrial static/dynamic simulations of used materials. After manufactured subunits were assembled in a factory, a series of executed six degree‐of‐freedom (DoF) displacements were measured by using a laser‐based dynamic tracking system (LDTS) for the initial validation. Deviations between measured and required displacements, referred to as displacement deviation, were used to evaluate the displacement accuracy of the chair. After satisfying the initial validation in the factory, the chair was disassembled and installed in our treatment room. The displacement accuracy of the chair was revalidated by using the LDTS. Then, an integration validation of the chair was conducted to position a head phantom by using our image‐guided radiotherapy (IGRT) system. Because the positioning accuracy of our IGRT system achieved a clinical tolerance of 1.0 mm and 1.0∘ only for a pitch/roll of <5∘, the integration validation was conducted on 36 planned fields with a 5∘ tilt evenly over 360∘ rotation. Results: To fulfill the general purpose of positioner, the chair allows the execution of any displacement over a cubic treatment volume with a length of 500 mm. Materials selected by simulations met required strengths under all circumstances of the clinical usage. The displacement accuracy of the chair satisfied the tolerance of 0.3 mm in‐translation and 0.3∘ in‐rotation during the initial validation in the factory. After the chair was installed in our institute, a linear displacement deviation of +/−0.6 mm was observed over +/−200 mm displacements in horizontal X/Y axes. After correcting the linear deviation, the displacement deviations of the chair for horizontal and vertical X/Y/Z axes were within 0.5 mm and 0.5∘ for its revalidation. During the integration validation, the displacement deviation of the chair was 0.8 mm and 0.6∘ when positioning a head phantom for the 36 fields with a 5∘ tilt. Conclusions: The chair achieved the required clinical tolerance for the clinical application. The tilt angle was limited to within 5∘ to treat patients through a specific treatment workflow with a proper daily quality assurance program during a clinical trial, started in May 2019. An integration validation with a 20∘ tilt will be conducted in the near future to realize the full potential of the isocentric rotating chair. [ABSTRACT FROM AUTHOR]

Background: Renal anemia is one of the most important complications in patients on maintenance hemodialysis (MHD). Telehealth-based dialysis registration systems have the advantage of real-time monitoring and have gradually been applied to the management of chronic diseases.Objective: The objective of our study was to evaluate the impact of a telehealth-based dialysis registration system on patients on MHD in terms of renal anemia control.Methods: The Red China project aimed to develop a dialysis registration system based on the WeChat mobile platform. Demographic and baseline laboratory parameters such as age, gender, primary disease, dialysis age, and baseline creatinine levels were recorded using this system. In addition, the hemoglobin and hematocrit levels were recorded monthly. The platform then generated a hemoglobin and hematocrit statistics report for each hemodialysis center monthly, including the detection rate, target rate, and distribution of hemoglobin and released it to physicians via the WeChat mobile phone app. The physicians were then able to treat the individual's anemia appropriately by changing the doses of erythropoiesis-stimulating agents or iron use on the basis of this report. We analyzed the demographic and baseline laboratory parameters, detection rate, target rate, and average level and distribution of hemoglobin 28 months after the launch of the project.Results: A total of 8392 patients on MHD from 28 hemodialysis centers in Shanghai were enrolled from June 2015 to October 2017. The detection rate of hemoglobin increased from 54.18% to 73.61% (P<.001), the target rate of hemoglobin increased from 47.55% to 56.07% (P<.001), and the mean level of hemoglobin increased from 10.83 (SD 1. 60) g/dL to 11.07 (SD 1.60) g/dL (P<.001). In addition, the proportion of patients with hemoglobin levels ≥11 g/dL but <13 g/dL increased from 40.40% to 47.48%.Conclusions: This telehealth-based dialysis registration system can provide timely reporting of the anemia status in patients on MHD, which may improve the awareness of anemia and the attention to and compliance with anemia monitoring. [ABSTRACT FROM AUTHOR]