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Background: There is an unmet need to assess research productivity from southeast Asia (SEA) regarding primary central nervous system (CNS) tumors. The country's economy, landscape of neurology practice, and disease burden are hypothesized to correlate with scientific output. This study aimed to objectively measure the impact of published studies on primary brain tumors in SEA and to assess for correlation with socioeconomic determinants and burden of disease. Methods: We systematically searched electronic databases for relevant articles from SEA on primary CNS tumor until July 31, 2020. Bibliometric indices were reported and subjected to correlational analysis with population size, gross domestic product (GDP) per capita, percentage (%) GDP for research and development (R&D), total number of neurologists, disease incidence, deaths, and disability-adjusted life years. Results: A total of 549 articles were included, consisting primarily of case reports (n=187, 34.06%) and discussed gliomas (n=195, 35.52%). Singapore published the most number of the articles (n=246, 44.8%). Statistical analysis showed a positive correlation between %GDP for R&D and total publication. Additionally, negative relationships were noted between burden of disease and total neurologist with most bibliometric indices. However, GDP per capita was not correlated with measures for research productivity. Conclusion: The low impact of scientific output on primary CNS tumors in SEA does not address the growing epidemiology and burden of this disease. An increase in the GDP growth and financial and manpower investment to R&D may significantly improve research productivity in SEA. [ABSTRACT FROM AUTHOR]

Background: The number of scientific publications on movement disorders from Southeast Asia (SEA) is thought to be low. Thus, we looked at the movement disorders research productivity among SEA countries and its associations with country-specific socioeconomic factors.Methods: We performed a systematic search for publications indexed in PubMed, Scopus, Embase and Cochrane Central Register of Controlled Trials from January 2000 to December 2019 with at least one author from SEA. Bibliometric indices were used to evaluate research impact. The country-specific socioeconomic characteristics were also obtained.Results: Of the 9488 identified articles, 1567 met the eligibility criteria. There was an increasing trend in the total number of publications on movement disorders during the last two decades. Singapore had the highest contribution in all aspects, which highlights the impact of knowledge-based economy type in research productivity. Parkinsonism remained the most studied condition, followed by dystonia, chorea, and tremor. Among the socioeconomic factors, only % gross domestic product (GDP) for research and development showed a positive correlation on the number of publications of a country. On the other hand, GDP per capita, population size and the number of neurologist size did not affect research productivity.Conclusions: An increasing trend in the movement disorders research output over the last 20 years was seen. Singapore had the highest contribution in all aspects which highlights the impact of economy in research productivity. Among the socioeconomic factors, only % GDP for R&D showed a positive impact on the number of publications of a country. [ABSTRACT FROM AUTHOR]

Background: Scientific output in Southeast Asia (SEA) on the topic of dementia is postulated to be low in quality and quantity. It is also speculated that certain socioeconomic variables and measures of disease burden for dementia may play a significant role in driving the research output of a particular country.Objective: This study aimed to determine the research impact of published journal articles on dementia in SEA and its association with country-level socioeconomic factors and measures of disease burden for dementia.Methods: A systematic search was conducted using electronic healthcare databases. We included articles published on dementia until August 2019 with at least 1 author affiliated with any SEA institution. We obtained bibliometric indices, relevant socioeconomic factors, and measures of disease burden for dementia from published sources.Results: One thousand six articles fulfilled the inclusion criteria. The majority of publications were related to Alzheimer's disease (n = 775, 77.0%). Singapore contributed the highest number of publications (n = 457, 45.4%). Gross domestic product (GDP) per capita, % GDP for research and development, and total neurologists significantly correlated with several bibliometric indices. On the other hand, the measures of disease burden for dementia in SEA countries were not significantly associated with research productivity.Conclusion: Research productivity in SEA on dementia has substantially increased in recent years. Augmenting GDP per capita and expanding the apportionment of resources to research and development (R&D) may have a significant role in the advancement of dementia research in SEA. [ABSTRACT FROM AUTHOR]