1. A Vision "Bolt-On" Item Could Increase the Discriminatory Power of the EQ-5D Index Score.
- Author
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Luo, Nan, Wang, Xingzhi, Ang, Marcus, Finkelstein, Eric A., Aung, Tin, Wong, Tien-Yin, and Lamoureux, Ecosse
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VISION disorders , *QUESTIONNAIRES , *CROSS-sectional method , *FACE-to-face communication , *ACQUISITION of data , *VISUAL acuity , *HEALTH status indicators , *QUALITY of life , *STATISTICS , *DATA analysis , *SEVERITY of illness index , *PSYCHOLOGY - Abstract
Background: Recently, a vision "bolt-on" EuroQol five-dimensional questionnaire (EQ-5D) was developed and tentative utility values (i.e., a "value set") for this new descriptive system were estimated.Objectives: To compare the discriminatory power of this bolt-on and standard utility-based EQ-5D health indices.Methods: Cross-sectional data on the (3-level) vision bolt-on EQ-5D were collected through face-to-face interviews with 500 and 336 individuals with and without visual impairment, respectively. To assess the discriminatory power of the vision bolt-on index relative to the standard EQ-5D index developed in the vision bolt-on valuation study, 16 pairs of mutually exclusive subgroups of individuals defined by the individuals' visual acuity and responses to the 14-item visual function questionnaire were compared pairwise. The absolute mean difference in the two index scores and the corresponding F statistic derived from the comparisons were used as measures of discriminatory power.Results: The absolute mean difference in the bolt-on index score was larger than that in the standard EQ-5D index score in 14 of the 16 comparisons. The bolt-on index score exhibited a larger F-statistic value than did the standard EQ-5D index score in all known-group comparisons, with the F-statistic ratio ranging from 0.415 to 0.770.Conclusions: The vision bolt-on EQ-5D appears to be more discriminative than the standard EQ-5D in measurement of vision problems. Future studies should investigate the extent to which the vision bolt-on item can increase the sensitivity of the EQ-5D to vision change in interventional studies. [ABSTRACT FROM AUTHOR]- Published
- 2015
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