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The objective of this study is to investigate tourism demand for Singapore using heterogeneous dynamic panel estimation methods. A binary variable representing the operation of Integrated Resorts (IRs), as well as income and real exchange rate, are included as determinants of tourism demand growth. Using seasonally adjusted and actual/raw quarterly data of 16 origin countries, our study shows that the pooled mran group (PMG) estimator is able to provide consistent and efficient estimates of long-run relationships between tourism demand and the determinants. The PMG results show that the long-run income (price) elasticity is positively (negatively) significant, with an elasticities range between 0.915 and 3.05 (−0.275 and −0.34). In addition, the study reveals that the IRs contribute to tourism demand growth, especially in attracting tourists from Asia. In the long term, tourism demand by the Asian markets is less income-sensitive than that of the non-Asian counterparts. [ABSTRACT FROM PUBLISHER]

Circular RNA (circRNA), one of the important non-coding RNA molecules with a closed-loop structure, plays a key regulatory role in cell processing. In this study, circRNAs of Epinephelus coioides , an important marine cultured fish in China, were isolated and characterized, and the network of circRNAs and mRNA was explored during Singapore grouper iridovirus (SGIV) infection, one of the most important double stranded DNA virus pathogens of marine fish. 10 g of raw data was obtained by high-throughput sequencing, and 2599 circRNAs were classified. During SGIV infection, 123 and 37 circRNAs occurred differential expression in spleen and spleen cells, indicating that circRNAs would be involved in the viral infection. GO annotation and KEGG demonstrated that circRNAs could target E. coioides genes to regulate cell activity and the activation of immune factors. The results provide some insights into the circRNAs mediated immune regulatory network during bony fish virus infection. • CircRNAs from Epinephelus coioides was identified and characterized. • The relationship of circRNA and mRNA was explored. • The function of E. coioides CircRNAs was evaluated during SGIV infection. [ABSTRACT FROM AUTHOR]