1. Constituents of Veltheimia viridifolia; I. Homoisoflavanones of the bulbs.
- Author
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Amschler G, Frahm AW, Hatzelmann A, Kilian U, Müller-Doblies D, and Müller-Doblies U
- Subjects
- Animals, Antioxidants chemistry, Antioxidants isolation & purification, Antioxidants pharmacology, Bronchodilator Agents chemistry, Bronchodilator Agents isolation & purification, Bronchodilator Agents pharmacology, Cattle, Guinea Pigs, Heart drug effects, Humans, In Vitro Techniques, Isoflavones chemistry, Isoflavones pharmacology, Leukocytes, Mononuclear drug effects, Leukotrienes biosynthesis, Molecular Structure, Phosphodiesterase Inhibitors chemistry, Phosphodiesterase Inhibitors isolation & purification, Phosphodiesterase Inhibitors pharmacology, South Africa, Isoflavones isolation & purification, Plants chemistry
- Abstract
The new homoisoflavanone R(-)-3-(4-hydroxybenzyl)-5-hydroxy-6, 7,8-trimethoxychroman-4-one (1) was isolated from the petroleum ether and the diethyl ether extracts of the bulbs of Veltheimia viridifolia (Hyacinthaceae) together with the known homoisoflavanone muscomin (2). The structures of the compounds were elucidated by means of 1H-NMR, 2D 1H-1H-COSY, 13C-NMR, HMQC, HMBC, mass, and CD spectra. Pharmacological testings of the new homoisoflavanone are reported.
- Published
- 1996
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