1. T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure.
- Author
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Iwase, Saori C, Edlefsen, Paul T, Bhebhe, Lynnette, Motsumi, Kesego, Moyo, Sikhulile, Happel, Anna-Ursula, Shao, Danica, Mmasa, Nicholas, Schenkel, Sara, Gasper, Melanie A, Dubois, Melanie, Files, Megan A, Seshadri, Chetan, Duffy, Fergal, Aitchison, John, Netea, Mihai G, Jao, Jennifer, Cameron, Donald W, Gray, Clive M, and Jaspan, Heather B
- Subjects
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TUBERCULOSIS epidemiology , *TUBERCULOSIS diagnosis , *HIV infections , *PRENATAL exposure delayed effects , *COMPARATIVE studies , *RESEARCH funding , *BLOOD testing , *ENVIRONMENTAL exposure , *FETUS - Abstract
Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9–18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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