1. Accelerated Biologic Aging, Chronic Stress, and Risk for Sepsis and Organ Failure Following Trauma.
- Author
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NeSmith, Elizabeth G., Medeiros, Regina S., Holsten Jr, Steven B., Zhu, Haidong, Looney, Stephen W., and Dong, Yanbin
- Subjects
INJURY complications ,AGING ,BIOMARKERS ,STATISTICAL correlation ,CYTOKINES ,EMERGENCY medical services ,INTERLEUKINS ,INTERVIEWING ,LONGITUDINAL method ,MULTIPLE organ failure ,PATIENTS ,QUESTIONNAIRES ,RESEARCH ,RISK assessment ,SEPSIS ,STATISTICS ,PHYSIOLOGICAL stress ,TUMOR necrosis factors ,TELOMERASE ,DATA analysis ,CONTINUING education units ,DESCRIPTIVE statistics ,SYSTEMIC inflammatory response syndrome ,DISEASE risk factors - Abstract
The article discusses a 2020 study on the potential pretrauma stress-posttrauma outcomes relationship. Results showed support for the hypothesis that pretrauma chronic stress accelerates biologic aging in trauma patients aged 18-44 years, with links to sepsis and organ failure susceptibility, and non-links to mean cytokine levels and chronic stress. Also noted are the results' possible identification of individuals at risk for such outcomes and of the appropriate interventions.
- Published
- 2020
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