1. Fluoroquinolone resistance among Streptococcus pneumoniae in Hong Kong linked to the Spanish 23F clone.
- Author
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Ho PL, Yam WC, Cheung TK, Ng WW, Que TL, Tsang DN, Ng TK, and Seto WH
- Subjects
- Adolescent, Adult, Anti-Bacterial Agents pharmacology, Child, Preschool, Electrophoresis, Gel, Pulsed-Field, Erythromycin pharmacology, Hong Kong epidemiology, Humans, Infant, Microbial Sensitivity Tests, Middle Aged, Penicillins pharmacology, Serotyping, Spain epidemiology, Streptococcus pneumoniae classification, Streptococcus pneumoniae genetics, Anti-Infective Agents pharmacology, Ciprofloxacin pharmacology, Drug Resistance, Multiple, Bacterial, Pneumonia, Pneumococcal epidemiology, Pneumonia, Pneumococcal microbiology, Streptococcus pneumoniae drug effects
- Abstract
Serotypes 6A/B, 19F, and 23F accounted for 73% of 140 mucosal isolates of Streptococcus pneumoniae from Hong Kong. In pulsed-field gel electrophoresis analysis, a group of related patterns was shared by 14 of 15 ciprofloxacin-resistant and 12 of 16 ciprofloxacin-susceptible isolates. These strains exhibited capsular switching and were highly similar to the Spanish 23F clone.
- Published
- 2001
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