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The Strengths and Difficulties Questionnaire (SDQ) is a well-known measuring instrument widely used for the assessment of mental health in children and adolescents. Relatively few studies have analysed the factor structure, the measurement invariance, and the internal consistency, including the information function of the SDQ in its parent version. The study included a large sample (N = 3828) from the Spanish National Survey (2016 were male; 52.7%). Mean age was 9.13 (SD = 3.21) with ages ranging from 4 to 14. The level of internal consistency of the scores for the Total difficulties score was 0.84, ranging between 0.75 and 0.78 for the SDQ subscales. Results from the confirmatory factor analysis showed a five-factor model as the most appropriate. Nonetheless, the fit indices were inadequate and different modifications were needed. The hypothesis of measurement invariance of the SDQ scores across gender and educational level was supported. The present study allows us to affirm that the SDQ, parent's version form, appears to be an adequate tool for the screening of emotional and behavioural problems for children and adolescents. Future research should analyse the SDQ at cross-cultural level, incorporating novel psychometric frameworks and new mental health classifications., (Copyright © 2017 Elsevier B.V. All rights reserved.)

Introduction: The main purpose of this study was to examine the prevalence of symptoms of an emotional and behavioral nature, as well as prosocial type capabilities, measured using the Strengths and Difficulties Questionnaire, in non-clinical adolescents., Method: The final sample was composed of a total of 508 students, 208 male (40.9%). The age of participants ranged from 11 to 18 years (M=13.91 years; SD=1.71)., Results: The results show that a significant number of adolescents self-reported emotional and behavioral problems. The mean scores of the Strengths and Difficulties Questionnaire subscales varied according the gender and age of the adolescents., Conclusions: In the present study, the prevalence of psychological difficulties among adolescents was similar to that reported in other national and international studies. In view of these results, there is a need to develop programs for the early detection of these types of problems in schools in children and adolescents ages., (Copyright © 2013 SEP y SEPB. Published by Elsevier España. All rights reserved.)

Relationship between thymic function and elderly survival has been suspected, despite the fact that formal proof is elusive due to technical limitations of thymic function-related markers. The newly described sj/β-TREC ratio allows now, by overcoming these limitations, an accurate measurement of thymic output in elderly humans. Thus, the aim of this study was to determine the impact of thymic function and inflammatory markers on healthy elderly human survival. Healthy volunteers (n = 151), aged over 65, were asked to participate (CARRERITAS cohort). Subjects were excluded if diagnosed of dementia or, during the last 6 months, had clinical data of infection, hospital admission, antitumor therapy, or any treatment that could influence the immune status. Thymic function (sj/β-TREC ratio), CD4:CD8 T cell ratio, C-reactive protein, interleukin-6, and neutrophilia were determined from basal samples. All basal variables and age were associated with 2-year all-cause mortality. Multivariate analysis showed that only thymic function and C-reactive protein were independently associated with time to death. In conclusion, we show, for the first time, the direct role of thymic function in human survival. C-reactive protein raise is also a marker of mortality in the healthy elderly, in a thymic-independent way.