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Objective. Early detection of oral infections plays an important role for dental referral during progression of renal disease and during dialysis treatment in uraemic patients. This study investigated how oral health is related to uraemia in a group of uraemic patients in Stockholm, Sweden. Material and methods. This cross-sectional study assessed oral diseases in chronic kidney disease (CKD) patients in different stages (n=93) compared with healthy age- and gender-matched controls. Differences in multiple oral outcomes, assessed by a dentist, were investigated in multivariate analyses, adjusted for tobacco habits, diabetes mellitus and uraemia status (predialysis, peritonealdialysis or haemodialysis). Results. Compared with healthy controls, uraemic patients had significantly worse dental status regarding the decayed, missing, filled teeth (DMFT) index (3.3, p=0.003), periodontal loss of attachment (0.9, p=0.00002) and periapical lesions (0.6, p=0.002). For haemodialysis patients DMFT (6.5, p=0.01), periodontal loss of attachment (2.2, p=0.007) and periapical lesions (1.0, p=0.01) were worse compared with controls. The differences between uraemic patients and controls remained after adjustment for age, gender, tobacco habits and diabetes (p<0.05 for all outcomes). Conclusions. Objective measurements showed that uraemic patients have more dental problems than healthy controls and the patients seem to develop their problems before they have progressed to dialysis. Therefore greater attention to dental problems may be warranted during the progression of uraemia to prevent deterioration of oral health. [ABSTRACT FROM AUTHOR]