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The author discusses the article by Sheena Rajesh Kakar and colleagues in this issue, on the high level of sexually transmissible infections (STI) in female commercial sex workers (CSW) in the western suburbs of Sydney, New South Wales. He is concerned that the deregulation of sex work in New South Wales, coupled with the lack of compulsory screening for sex workers in legal industries have led to increased rates of Chlamydia (C) trachomatis in the CSW. The author urges for more studies of female CSW at higher risk of STI.