1. High-resolution fast-tomography brain-imaging beamline at the Taiwan Photon Source.
- Author
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Chen HH, Yang SM, Yang KE, Chiu CY, Chang CJ, Wang YS, Lee TT, Huang YF, Chen YY, Petibois C, Chang SH, Cai X, Low CM, Tan FCK, Teo A, Tok ES, Lim JH, Je JH, Kohmura Y, Ishikawa T, Margaritondo G, and Hwu Y
- Subjects
- Animals, Equipment Design, Photons, Synchrotrons, Taiwan, Brain diagnostic imaging, Imaging, Three-Dimensional, Radiation Injuries prevention & control, X-Ray Microtomography instrumentation
- Abstract
The new Brain Imaging Beamline (BIB) of the Taiwan Photon Source (TPS) has been commissioned and opened to users. The BIB and in particular its endstation are designed to take advantage of bright unmonochromatized synchrotron X-rays and target fast 3D imaging, ∼1 ms exposure time plus very high ∼0.3 µm spatial resolution. A critical step in achieving the planned performances was the solution to the X-ray induced damaging problems of the detection system. High-energy photons were identified as their principal cause and were solved by combining tailored filters/attenuators and a high-energy cut-off mirror. This enabled the tomography acquisition throughput to reach >1 mm
3 min-1 , a critical performance for large-animal brain mapping and a vital mission of the beamline.- Published
- 2021
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