1. Survival rate prediction of breast cancer patients of 0-IV stages with and without radiotherapy via a revised Taylor series expansion algorithm: A population-based study in Taiwan.
- Author
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Chiu, Shao-Wen, Peng, Jia-Feng, Wang, Tzu-Hwei, Pan, Lung-Fa, Pan, Lung-Kwang, Gómez, Carlos, and Schwarzacher, Severin P.
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BREAST cancer treatment , *CANCER radiotherapy , *TAYLOR'S series , *ALGORITHMS , *PREDICTION models , *BREAST cancer prognosis , *BREAST tumors , *STATISTICAL models - Abstract
Background: The morbidity of breast cancer has continuously achieved a global topicality. In particular, during the last decade several ten thousand female adults in Taiwan have been confirmed as breast cancer patients.Objective: To predict the survival rate of breast cancer patients at various (0-IV) stages and provide efficient assessment of proposed radiotherapy for patients.Methods: The prediction algorithm proposed is based on the revised hit and target model and implies the application of Taylor series expansion to the population-based survey dataset. The proposed algorithm features a specific function comprising a single simple exponential term exp(-αt) to imply the fundamental degradation of patient's health multiplied by an additional term P(αt), which specifies the recovery effect of a particular therapy.Results: Its calculated values for breast cancer patients who undergone radiotherapy at different stages 0-IV were {0.0029, 0.0066, 0.0178, 0.0475, 0.1785} yr-1, respectively, while those for corresponding groups of patients with no radiotherapy were assessed as {0.0072, 0.0137, 0.0264, 0.0913, 0.2425} yr-1.Conclusions: The revised algorithm successfully interpreted the breast cancer patients' survival rate at stages 0-IV and evaluated the necessity of radiotherapy for patients at various stages as well. [ABSTRACT FROM AUTHOR]- Published
- 2019
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