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Charcoal rot caused by Macrophomina phaseolina (MP) is the most important disease that limits sorghum dryland production in northern Tamaulipas, Mexico. Grain yield losses caused by MP are approximately 30%. The objective of this study was to evaluate the response of experimental and commercial hybrids to MP and identify MP tolerant progenitors. Experimental hybrids RB-118 x 435 and RB-27 x 437 showed MP tolerance and grain field similar to commercial checks Pioneer 82G63, Pioneer 84G62, RB-Patrón, Asgrow Z- 400, RB-3030, and DK-47, and greater than Asgrow-Ámbar. Progenitor females that produced tolerant MP hybrids were LRB-118 and R-27, and males Tx-435 and Tx-437. [ABSTRACT FROM AUTHOR]