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A study is presented of 356 patients with viral hepatitis A (age: 16-35 years); 256 of them lived in a zone of industrially caused contaminations of the atmospheric air and 100 (control group) lived in rural districts. Of the main group 106 patients were given during the acute period basis treatment plus quercetin, splenin, sodium nucleinate and glyciram. It was found that in those living in ecologically unfavourable regions viral hepatitis A had a more severe course, the disease was protracted, recurrences were more frequent, immune disorders were pronounced and long-standing. Use of immunocorrective and hepatoprotecting treatment resulted in an essential improvement of the clinical and immunological indices.

A total of 50 patients, who had suffered from acute radiation sickness (I-III degree of severity) as a result of the accident at the Chernobyl Nuclear Power Plant, were followed up for hematological changes. The absorbed dose of relatively even gamma-irradiation assessed by karyometry fluctuated from 0.5 to 5.7 Gy. In 17 of the patients the influence of lithium carbonate on the course of radiation neutropenia was evaluated. No appreciable effect of the agent administration in a dose of 900 mg/patient/day was recorder from 9 to 42 day after irradiation. The authors have also considered the correlations of the values of irradiation doses calculated by varying methods of biological dosimetry.