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Talaromyces marneffei and other Talaromyces species can cause opportunistic invasive fungal infections. We characterized clinical Talaromyces isolates from patients in California, USA, a non-Talaromyces-endemic area, by a multiphasic approach, including multigene phylogeny, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, and phenotypic methods. We identified 10 potentially pathogenic Talaromyces isolates, 2 T. marneffei. [ABSTRACT FROM AUTHOR]

The article reflects on an approach for analyzing biological molecules under the Section 103 of the Title 35 of the U.S. Code. It discusses earlier events in the U.S. patent law and the potential effects of the Supreme Court's decision in the court case Mayo Collaborative Services v. Prometheus Laboratories. It mentions that patent eligibility of human genes is examined which concluded that isolated human genes are not patentable.

A calendar of events related to biomolecular screening in 2010 is presented, including the 12th Belgian Organic Synthesis Symposium in Namur in July, The American Chemical Society (ACS) National Meeting in Boston, Massachusetts in August and Pacifichem 2010 in Honolulu, Hawaii in December.