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1. Novel immune checkpoint blocker approved for the treatment of advanced melanoma.

Author

Galluzzi, Lorenzo, Kroemer, Guido, and Eggermont, Alexander

Subjects
*DRUG approval, *PEMBROLIZUMAB, *MONOCLONAL antibodies, *CLINICAL trials, *MELANOMA, *PATIENTS
Abstract

The author reflects on the approval of the U.S. Food and Drug Administration (FDA) on pembrolizumab, a monoclonal antibody that targets programmed cell death 1 (PDCD1). The author states that the antibody was granted upon disclosure of safety and efficacy results from clinical trial conducted on 173 participants with advanced melanoma. The author mentions that the pembrolizumab adds to therapeutic options for patients with melanoma who failed to respond to other medications.

Published
2014
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