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1. Implementing large-scale ENU mutagenesis screens in North America.

Author

Clark AT, Goldowitz D, Takahashi JS, Vitaterna MH, Siepka SM, Peters LL, Frankel WN, Carlson GA, Rossant J, Nadeau JH, and Justice MJ

Subjects
Animals, Disease Models, Animal, Ethylnitrosourea, Female, Male, National Institutes of Health (U.S.), Nervous System Diseases genetics, Phenotype, United States, Chromosome Mapping, Mice genetics, Mutation
Abstract

A step towards annotating the mouse genome is to use forward genetics in phenotype-driven screens to saturate the genome with mutations. The purpose of this article is to highlight the new projects in North America that are focused on isolating mouse mutations after ENU mutagenesis and phenotype screening.

Published
2004
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