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The article reports on medical cases of postvaccination syncope in adolescents in the U.S. from January 2005 to July 2007. Analyses were done by the Centers for Disease Control and Prevention and the Food and Drug Administration using data from the Vaccine Adverse Event Reporting System. Details on the number of postvaccination episodes by selected characteristics are presented. Also noted are the four limitations of the analyses.

The article presents a report from the U.S. Centers of Disease Control and Prevention regarding the incidence of syncope or fainting following vaccination in the U.S. between January 2005 and July 2007. Findings reveal the number of postvaccination syncope events in females aged 11-18 years has increased since the licensing of vaccines to treat quadrivalent human papillomavirus and other vaccines commonly used to treat adolescents. The Advisory Committee on Immunization Practices recommends observing patients for 15 minutes after vaccination. Several syncope case studies involving girls who received vaccinations are presented.