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Your search keyword '"Pestalozzi, Bernhard C."' showing total 1 results
Start Over Author "Pestalozzi, Bernhard C." Region united states
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1. Cell Cycle Regulation of the G[sub 0]/G[sub1] Transition in 5-Fluorouracil-Sensitive and -Resistant Human Colon Cancer Cell Lines.

Author

McGinn, Cornelius J., Pestalozzi, Bernhard C., Drake, James C., Glennon, M. Clay, Kunugi, Keith, Otterson, G., Allegra, Carmen J., Johnston, Patrick G., and Kinsella, Timothy J.

Subjects
CANCER cell growth, COLON cancer, CELL cycle, FLUOROURACIL
Abstract

Examines the cell cycle regulation in 5-fluorouracil(5-FU)-resistant colon cancer cell lines in the United States. Association of 5-FU resistance with thymidylate synthase (TS) gene amplification and TS protein levels; Impact of TS levels on cell cycle progression; Methods to overcome 5-FU resistance; Expression of TS enzyme in resistance development.

Published
2000

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