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Hypertension is a main cause of death in the United States with more than 103 million adults affected. While pharmacological treatments are effective, blood pressure (BP) remains uncontrolled in 50–60% of resistant hypertensive subjects. Using a custom-wired miniature electrode, we previously reported that deep peroneal nerve stimulation (DPNS) elicited acute cardiovascular depressor responses in anesthetized spontaneously hypertensive rats (SHRs). Here, we further study this effect by implementing a wireless system and exploring different stimulation parameters to achieve a maximum depressor response. Our results indicate that DPNS consistently induces a reduction in BP and suggests that renal sympathetic nerve activity (RSNA) is altered by this bioelectronic treatment. To test the acute effect of DPNS in awake animals, we developed a novel miniaturized wireless microchannel electrode (w-μCE), with a Z-shaped microchannel through which the target nerves slide and lock into the recording/stimulation chamber. Animals implanted with w-μCE and BP telemetry systems for 3 weeks showed an average BP of 150 ± 14 mmHg, which was reduced significantly by an active DPNS session to 135 ± 8 mmHg (p < 0.04), but not in sham-treated animals. The depressor response in animals with an active w-μCE was progressively returned to baseline levels 14 min later (164 ± 26 mmHg). This depressor response was confirmed in restrained fully awake animals that received DPNS for 10 days, where tail-cuff BP measurements showed that systolic BP in SHR lowered 10% at 1 h and 16% 2 h after the DPNS when compared to the post-implantation baseline. Together, these results support the use of DPN neuromodulation as a possible strategy to lower BP in drug-resistant hypertension. [ABSTRACT FROM AUTHOR]

This study, grounded in the theory of diffusion, utilizes a qualitative phenomenological methodology to understand perspectives of parents and school personnel on the implementation of tiplines and/or reporting apps for school safety. Barriers and facilitators for the development and successful implementation of Advocatr, a school-based tipline/reporting app were identified. Adult participants were recruited from four U.S. high schools. These participants attended one of three sets of focus groups (parents, staff, and administrators) at two time points (Wave 1: n = 56; Wave 2: n = 55). Results indicated that parents and school staff are primarily concerned about mental health as a school safety issue. While many thought school tiplines could be useful, they identified improvements that could support its successful development and implementation such as school-wide training and school climate improvement frameworks. Implications for practice, policy, and future research addressing school safety are discussed. [ABSTRACT FROM AUTHOR]

Latinx youths continue to have the highest rates of teenage births in the United States and are at increased risk of acquiring sexually transmitted infections, including HIV/AIDS. A community-based research partnership piloted Families Talking Together, a brief, parent-based sexual risk reduction program using a novel and culturally relevant approach. This mixed-methods study examined the feasibility and acceptability of Spanish-speaking promotoras de salud (that is, community health workers) as implementers of an evidence-based intervention (EBI) to reach underserved immigrant communities. Findings suggest that promotoras are capable of implementing the EBI with positive organizational, client, and implementation outcomes. Furthermore, promotoras hold particular promise for addressing reproductive health disparities as they are indigenous and trusted members of the community who can reach members of marginalized Latino populations. [ABSTRACT FROM AUTHOR]

To improve the coordination of long-term services and supports for dual-eligibles (those with both Medicare and Medicaid), California created Cal MediConnect (CMC), an Affordable Care Act-authorized managed care demonstration program. Beneficiaries were "passively enrolled" into CMC, meaning they were automatically enrolled unless they actively opted out. The aim of this study was to examine differences in factors influencing the enrollment decisions of U.S. born and immigrant dual-eligible beneficiaries. To explore differences in decision-making processes, we conducted in-depth interviews with dual-eligible consumers (39 native and 14 immigrant) in Los Angeles County. Interviews were analyzed using a constructivist grounded theory approach. Our findings illustrate a heightened sense of vulnerability and disempowerment experienced by immigrant participants. Immigrant participants also faced greater challenges in accessing healthcare and eliciting healthcare information compared to U.S.-born participants. Understanding the diverse perspectives of dual-eligible immigrant healthcare decision-making has implications for health care reform strategies aimed at ameliorating disparities for vulnerable immigrant populations. [ABSTRACT FROM AUTHOR]

Objectives: In 2014, there were 21.5 million Americans (12 years old or older) that had a substance abuse disorder and almost 2 million of them had a substance use disorder involving prescription pain relievers (SAMHSA, 2014). The misuse of non-medical pain medication (NMPM) is a significant public health problem. This study examines the impact of individual-level social capital in non-medical use of pain medications (NMPM) among individuals 50 years or older. Methods: Data from the 2003 National Survey on Drug Use and Health (n = 11,146) was analyzed using bivariate analysis and logistic regression analysis. Results: Perception of social capital varied by race/ethnicity; White respondents reported the highest rates of non-medical use of pain medications (NMPM) in the past year and lifetime. Social capital was associated with a decrease in the likelihood of NMPM across the various groups in the sample. Discussion: Features of social capital were associated with likelihood of non-medical use of pain medications. Future research should focus on understanding the mechanisms by which these features of social capital impact NMPM among diverse groups. [ABSTRACT FROM AUTHOR]

Microbial processes are critical to the function of freshwater ecosystems, yet we still do not fully understand the factors that shape freshwater microbial communities. Furthermore, freshwater ecosystems are particularly susceptible to effects of environmental change, including influx of exogenous nutrients such as nitrogen and phosphorus. To evaluate the impact of nitrogen loading on the microbial community structure of shallow freshwater lakes, water samples collected from Lake Shenandoah (Virginia, USA) were incubated with two concentrations of either ammonium, nitrate, or urea as a nitrogen source. The potential impact of these nitrogen compounds on the bacterial community structure was assessed via 16S rRNA amplicon sequencing. At the phylum level, the dominant taxa in Lake Shenandoah were comprised of Actinobacteria and Proteobacteria, which were not affected by exposure to the various nitrogen treatments. Overall, there was not a significant shift in the diversity of the bacterial community of Lake Shenandoah with the addition of nitrogen sources, indicating this shallow system may be constrained by other environmental factors. [ABSTRACT FROM AUTHOR]

An editorial is presented which addresses the authors' claim that public policies are needed to address the Latino immigrant workforce in the U.S. as of 2019, and it mentions how changes in immigration patterns and demographics in America are impacting the needs of immigrants and American citizens. Immigrant workers from Mexico, Central America, and Caribbean nations are examined, along with uninsured Latino immigrants, access to health care, and education policies.

The extent to which the 8-wk U.S. Army Basic Combat Training (BCT) course elicits or exacerbates menstrual dysfunction (MD) and mechanisms behind this dysfunction is not clear. Purpose: To determine whether changes in menstruation develop in female trainees during BCT and whether changes in body mass, body composition and/or physical activity are associated with menstrual interruption during BCT. Methods: Female trainees grouped according to self-reported menstrual status in the 12 months before BCT as having regular cycles (RC; n = 352) or MD (n = 97) completed height, body mass, and body composition assessments and questionnaires before and after BCT. Fisher's exact test and Mann-Whitney U test were used to compare between-group differences in categorical and continuous variables, respectively. Among RC trainees, odds ratios were calculated to examine the influence of changes in body mass, lean mass, and fat mass on a trainee's likelihood to miss a period during BCT. Results: There were no differences in race, height, body mass, body mass index, or physical activity history at pre-BCT between RC and MD (P >0.05). Overall, 86% of trainees experienced changes to menstruation during BCT. RC were more likely than MD to have at least one period during BCT (81% vs 69%, respectively, P = 0.01). Among RC, gaining more body mass and lean mass and losing less fat mass were associated with increased odds of missing a period during BCT. Conclusions: These findings demonstrate that most female trainees experience menstrual changes during BCT. Menstrual cycle interruptions do not appear to align with loss of body or fat mass. [ABSTRACT FROM AUTHOR]

The article offers information on the legislative history, purpose and significance of the New York Prudent Management of Institutional Funds Act (NYPMIFA), which was signed into law by New York Governor David Patterson on September 17, 2010. It informs that the NYPMIFA addresses the law governing investment management and appropriation of charitable and not-for-profit assets held by not-for-profit corporations in New York. It distinguishes the provisions of the NYPMIFA with the Uniform PMIFA.

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Despite the rise in anti-Islamic sentiment, Muslim youth's experiences of religious discrimination are under researched. The goal of this paper is to better understand the complexities associated with religious discrimination for youth and adolescents and how to mitigate the harm caused by these discriminatory experiences. This mixed methods systematic review consists of 44 qualitative and quantitative studies from 34 journals, discussing experiences of religious discrimination for participants ages 4–25 both in the United States and internationally. This review discussed student experiences, the context of school as a conduit for discrimination, how students responded to these instances, including protective factors and recommendations for future research and policy. Impact Statement This article systematically examined experiences of discrimination faced by Muslim students in Pre-K–12 and university settings. The results have implications for researchers, policymakers, and school staff on how to mitigate discriminatory acts toward Muslim students to create a safe and inclusive school environment for all students. Educators and school staff must work on reducing their individual and classroom biases through cultural competence training and a more inclusive curriculum. Policymakers should work to create inclusive practices that promote equity for Muslim students, and researchers should conduct additional projects to better understand the scope and outcomes associated with Islamophobia in schools. [ABSTRACT FROM AUTHOR]

Begomovirus spp. cause substantial losses in bean crops in tropical and subtropical regions of the Americas. The predominant Begomovirus sp. in Central America associated with golden mosaic symptoms in bean is Bean golden yellow mosaic virus (BGYMV). However, Calopogonium golden mosaic virus was previously found to infect bean crops in the northern region of Costa Rica. The objective of this research was to identify Begomovirus spp. that infect bean plants in different geographical regions of Nicaragua. In all, 126 samples of young bean leaves with symptoms of golden mosaic were collected from eight different regions of Nicaragua. Using DNA hybridization with specific probes, 120 samples tested positive for BGYMV, 14 samples tested positive for Squash yellow mild mottle virus, and 7 samples tested positive for Calopogonium golden mosaic virus. Sequence analysis of polymerase chain reaction-amplified products from three samples (MA-9 Managua, BE-8 Rivas, and SO-9 Granada) also indicated that the symptoms of golden mosaic in bean are associated with viral sequences from three different Begomovirus spp. Management of bean golden mosaic disease must take into account that BGYMV is the predominant virus (95% of the samples) and that 12% of the samples exhibited possible mixed infections or recombination events in the south and central geographical regions of Nicaragua. [ABSTRACT FROM AUTHOR]

Data from the 2003 National Survey on Drug Use and Health was utilized to elucidate the relationship between individual-level social capital and illicit drug use among racial/ethnic groups. Analysis of variance indicated that Whites had different perceptions of social capital compared to other groups, in measures of social participation, neighborhood cohesion, trust, and norms of reciprocity. Logistic regression analysis showed that individual-level social capital, measured by trust and norms of reciprocity, was weakly associated with illicit drug use. However, individuals with higher social participation were less likely to have used illicit drugs ever or during the month prior to the interview. The association between social capital and illicit drug use is discussed, as well as the role of social participation in illicit drug use. Rather than an individual-level measure of social capital, future research should employ a neighborhood-level measure of social capital that aggregates neighborhood cohesion, trust, norms of reciprocity, and social participation. [ABSTRACT FROM AUTHOR]

Abstract: Context: Epidemiologic studies of obesity have not examined the prevalence and relationship of mental health conditions with obesity for diverse ethnic and racial populations in the United States. Objective: (1) To assess whether obesity was associated with diverse psychiatric diagnoses across a representative sample of non-Latino whites, Latinos, Asians, African-Americans, and Afro-Caribbeans; and (2) to test whether physical health status, smoking, sociodemographic characteristics, and psychiatric comorbidities mediate any of the observed associations. Design: Our analyses used pooled data from the NIMH Collaborative Psychiatric Epidemiology Surveys (CPES). Analyses tested the association between obesity and psychiatric disorders in a diverse sample of Americans (N=13,837), while adjusting for factors such as other disorders, age, gender, socioeconomic status, smoking and physical health status (as measured by chronic conditions and WHO-DAS scores) in different models. Results: The relationship between obesity and last-year psychiatric disorders varied by ethnicity/race. The likelihood of having mood or anxiety disorder was positively associated with obesity for certain racial/ethnic groups, but was moderated by differences in physical health status. Substance-use disorders were associated with decreased odds for obesity in African-Americans. Conclusions: The role of physical health status (as measured by chronic conditions and WHO-DAS scores) dramatically changes the pattern of associations between obesity and psychiatric disorders, suggesting the important role it plays in explaining differential patterns of association across racial and ethnic groups. [Copyright &y& Elsevier]

The article summarizes a poster presentation on the assessment of reflective function (RF) in psychoanalysis using a multidimensional rating scale presented at the 6th annual poster session of the American Psychoanalytic Association. A Reflective Function Rating Scale (RFRS) was developed and its reliability and validity were measured based on the results of the RF scores obtained via the Adult Attachment Interview (AAI). Patients who were subjected to different treatments for borderline personality disorder were involved in the study.

Cluster-based studies involving aggregate units such as hospitals or medical practices are increasingly being used in healthcare evaluation. An important characteristic of such studies is the presence of intracluster correlation, typically quantified by the intracluster correlation coefficient (ICC). Sample size calculations for cluster-based studies need to account for the ICC, or risk underestimating the sample size required to yield the desired levels of power and significance. In this article, we present values for ICCs that were obtained from data on 97 095 pregnancies and 98 072 births taking place in a representative sample of 120 hospitals in eight Latin American countries. We present ICCs for 86 variables measured on mothers and newborns from pregnancy to the time of hospital discharge, including ‘process variables’ representing actual medical care received for each mother and newborn. Process variables are of primary interest in the field of implementation research. We found that overall, ICCs ranged from a minimum of 0.0003 to a maximum of 0.563 (median 0.067). For maternal and newborn outcome variables, the median ICCs were 0.011 (interquartile range 0.007–0.037) and 0.054 (interquartile range 0.013–0.075) respectively; however, for process variables, the median was 0.161 (interquartile range 0.072–0.328). Thus, we confirm previous findings that process variables tend to have higher ICCs than outcome variables. We demonstrate that ICCs generally tend to increase with higher prevalences (close to 0.5). These results can help researcherscalculate the required sample size for future research studies in maternal and perinatal health. [ABSTRACT FROM AUTHOR]

OBJECTIVES: To examine the prevalence and effects of diabetes mellitus in a subgroup of older Mexicans to allow comparisons to older persons of Mexican origin living in the United States. DESIGN: Longitudinal study. SETTING: High-rise retirement housing in Mexico City. PARTICIPANTS: Seven hundred eighty-five public servants and their family members aged 65 and older. MEASUREMENTS: Geriatric survey of function; mental status and depression; a physical examination; and blood samples for glucose and cholesterol. RESULTS: The prevalence of diabetes mellitus in this population was 15.1%, substantially lower than the prevalence reported in people of Mexican origin living in the United States. Nondiabetics were more obese than diabetics. Diabetes mellitus was more common in men than women. The mortality rate was greater in diabetics than nondiabetics (relative risk = 1.73, P < .05). Diabetics had more coronary artery disease and were more likely to die from myocardial infarction and neoplasms than nondiabetics. Diabetics were more likely to be functionally impaired (P < .0001) but no more likely to fall or to have fractures. Diabetics did not differ from nondiabetics in cognitive impairment or level of dysphoria. CONCLUSION: These studies highlight some important similarities and differences in comparing a middle class subgroup of older diabetics in Mexico City with diabetics of Mexican origin living in the United States. [ABSTRACT FROM AUTHOR]

Presents information on a study which examined the factors that contributed significantly to higher blood lead levels in an inner-city population of pregnant women in South Central Los Angeles, California. Subjects of the study; Details on blood lead measurements; Results and discussion.