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The article focuses on the relation of brown recluse spiders' population distribution in the southern and eastern area of U.S. to the diagnosis of laxoscelism. According to the conducted study, the diagnoses of loxoscelism are often conducted on the areas where the spiders are uncommon and rare. It discusses the clinical study on the connection of spiders in necrotic skin lesion. It presents the clinical importance of spiders in the medical field as an anti-venom on poisons.

Abstract: Bites by the woodlouse spider, Dysdera crocata, are virtually innocuous. The main symptom is minor pain, typically lasting less than 1h, probably due mostly to mechanical puncture of the skin. However, because the spider has a strong proclivity to bite, has large fangs which it bares when threatened and is commonly mistaken for the medically important brown recluse spider in the United States, documentation of the mild effects of its bites may prevent excessive, unwarranted and possibly harmful treatment. We present information on eight verified bites reported to us as well as eight additional bites recorded in the literature. [Copyright &y& Elsevier]

Reports a case of arachnid envenomation from the brown recluse spider in the United States. Variation in the severity of the bites; Systemic symptoms; Treatment options.

Envenomations are an important cause of injury in the Americas. While supportive care alone may result in an acceptable outcome, antivenom offers a specific therapy that can significantly reduce the injury and symptoms of the envenomation. Antivenoms are hyperimmune sera collected from animals immunised with venom. The antibodies contained in the serum bind and inactivate venom components. This leads to cessation or reversal of the toxic effects of the venom. The serum is often processed to increase the level of antibodies directed against venom components and decrease the amount of inactive proteins that may cause allergic reactions. The processing may include precipitation of inactive proteins, chromatographic methods and cleavage of the immunoglobulins to form antibody fragments known as Fab or F(ab)[SUB2]. In the Americas, antivenoms are produced to treat crotalid and Micrurus snake envenomations, Latrodectus and Loxosceles spider envenomations and Centruroides and Tityus scorpion envenomations. The indications, method of administration and incidence of adverse reactions differ greatly for each antivenom. The adverse effects encountered when using antivenoms are primarily allergic in nature. Anaphylaxis, which may be life threatening, is a major concern. Preparations to treat anaphylaxis must be made before initiating antivenom therapy. Serum sickness is also common with many of the antivenom preparations. [ABSTRACT FROM AUTHOR]

An 8-year-old boy with multiple (up to 12) hemorrhagic and necrotic blisters was eventually diagnosed as being the victim of probable spider bites. Arachnidism, specifically loxoscelism (brown recluse spider bite), is unusual in the northeastern United States. [ABSTRACT FROM AUTHOR]

Reports that toxicity from a bite of the black widow spider or related species of the genus Latrodectus accounts for the majority of cases of arachnidism in the U.S. Complication of necrotic arachnidism caused by Loxosceles bites; Symptoms of Loxosceles bite; Investigation of a case of spider bite with severe hemolytic reaction.

The article focuses on the rise of number of black widow spider in Texas. A chart depicts the monthly number of spider bites reported in the state poison centers during 2008-2011. The black widow spider is one of the most dangerous spiders in the U.S., and it inhabits in dry, dark, protected environments outdoors or in basements, sheds, and garages.

The article discusses several myths and facts about brown recluse spider bites. One myth about brown recluse spider bites is that a patient do not need to seek medical attention. Anyone bitten by the spider should see the primary care provider immediately. Another myth is that the brown recluse spider is common throughout the U.S. Another myth is that the bite always causes necrosis and tissue loss.